宫颈病变中HPV DNA检测与IHC检测P16蛋白的关联性研究

王皓晨, 贾利晴, 杨瑜, 王乾, 郁成礼, 田田, 毕蕊, 涂小予, 柏乾明, 朱晓丽, 周晓燕, 任敏

A study on the correlation between HPV DNA and IHC P16 expression in cervical lesions

WANG Haochen, JIA Liqing, YANG Yu, WANG Qian, YU Chengli, TIAN Tian, BI Rui, TU Xiaoyu, BAI Qianming, ZHU Xiaoli, ZHOU Xiaoyan, REN Min

图3 宫颈胃型腺癌IHC-P16与HPV结果不一致病例

Fig. 3 The case of gastric type cervical adenocarcinoma discrepant findings between IHC-P16 and HPV A: Gastric type cervical adenocarcinoma, non-HPV associated adenocarcinoma (H-E staining, ×20); B: P16 immunostaining showed negitive staining in the tumors; C: A representative PCR positive for HR-HPV DNA; D: Gastric type cervical adenocarcinoma, non-HPV associated adenocarcinoma (H-E staining, ×20); E: P16 immunostaining showed positive staining in the tumors; F: A representative PCR negitive for HR-HPV DNA.