Clinical utility of circulating tumor DNA detection for diagnosis of breast cancer

叶　青; 江泽飞

doi:10.19401/j.cnki.1007-3639.2016.11.012

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Clinical utility of circulating tumor DNA detection for diagnosis of breast cancer

更新时间：2025-12-31

- Clinical utility of circulating tumor DNA detection for diagnosis of breast cancer
- China Oncology Vol. 26, Issue 11, Pages: 947-951(2016)
- 作者机构：
  
  军事医学科学院附属医院乳腺肿瘤科,北京,100071
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2016.11.012
  CLC：
- Published Online：22 January 2017，
  
  Published：22 January 2016
- 稿件说明：
移动端阅览
叶　青,江泽飞. 循环肿瘤DNA检测在乳腺癌诊断中的临床应用[J]. 中国癌症杂志, 2016, 26(11): 947-951.

叶　青, 江泽飞. Clinical utility of circulating tumor DNA detection for diagnosis of breast cancer[J]. China Oncology, 2016, 26(11): 947-951.
叶　青,江泽飞. 循环肿瘤DNA检测在乳腺癌诊断中的临床应用[J]. 中国癌症杂志, 2016, 26(11): 947-951. DOI： 10.19401/j.cnki.1007-3639.2016.11.012.

叶　青, 江泽飞. Clinical utility of circulating tumor DNA detection for diagnosis of breast cancer[J]. China Oncology, 2016, 26(11): 947-951. DOI： 10.19401/j.cnki.1007-3639.2016.11.012.

摘要

随着二代测序技术的发展，循环肿瘤DNA(circulating tumor DNA，ctDNA)检测在乳腺癌中的应用得到越来越多的关注。目前国内外大量研究显示ctDNA检测技术在监测肿瘤负荷、疗效预测、早期诊断、预后分析等方面具有广阔的应用价值。在乳腺癌诊疗走向个体化精准的时代，ctDNA检测能够为患者提供更为精准的诊断，指导临床治疗。

Abstract

With the development of the next generation sequencing technology

considerable attention has been paid to the utility of circulating tumor DNA (ctDNA) detection in breast cancer. There are many clinical trials showed the ctDNA detection is a potential biomarker for the diagnosis

management and prognosis of breast cancer. ctDNA detection can provide a more accurate diagnosis for patients to guide clinical treatment in precision medicine era.

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