Research progress on circulating tumor biomarkers in prostate cancer

李高翔; 杨云杰; 戴　波

doi:10.19401/j.cnki.1007-3639.2017.10.012

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Research progress on circulating tumor biomarkers in prostate cancer

更新时间：2025-12-31

- Research progress on circulating tumor biomarkers in prostate cancer
- China Oncology Vol. 27, Issue 10, Pages: 833-838(2017)
- 作者机构：
  
  复旦大学附属肿瘤医院泌尿外科，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2017.10.012
  CLC：
- Published Online：05 December 2017，
  
  Published：05 December 2017
- 稿件说明：
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李高翔,杨云杰,戴　波. 循环肿瘤标志物在前列腺癌研究中的新进展[J]. 中国癌症杂志, 2017, 27(10): 833-838.

李高翔, 杨云杰, 戴　波. Research progress on circulating tumor biomarkers in prostate cancer[J]. China Oncology, 2017, 27(10): 833-838.
李高翔,杨云杰,戴　波. 循环肿瘤标志物在前列腺癌研究中的新进展[J]. 中国癌症杂志, 2017, 27(10): 833-838. DOI： 10.19401/j.cnki.1007-3639.2017.10.012.

李高翔, 杨云杰, 戴　波. Research progress on circulating tumor biomarkers in prostate cancer[J]. China Oncology, 2017, 27(10): 833-838. DOI： 10.19401/j.cnki.1007-3639.2017.10.012.

摘要

前列腺癌是最常见的恶性肿瘤之一，虽然前列腺特异性抗原(prostate-specific antigen，PSA)筛查、综合治疗的开展使其早期诊断、治疗疗效有较大改善，但若实现前列腺癌的个体化治疗仍亟需新的生物标志物。循环肿瘤标志物来源于肿瘤组织，与肿瘤转移及预后密切相关。该研究对循环肿瘤标志物的检测方法及其在前列腺癌研究中的新进展进行综述。

Abstract

Prostate cancer is one of the most common malignant tumors. Although (prostate-specific antigen

PSA) screening and multidisciplinary therapy had largely improved the therapy effects

new biological markers are needed to achieve individual treatment for prostate cancer. Circulating tumor biomarkers originate from primary tumor tissues and have close relationship with cancer metastases and prognosis. This review summarized the circulating tumor biomarkers detection methods and relevant clinical research in recent years.

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