Recent advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2017

张师容; 靳　伟; 刘　亮

doi:10.19401/j.cnki.1007-3639.2018.01.001

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Recent advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2017

更新时间：2026-01-27

- Recent advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2017
- China Oncology Vol. 28, Issue 1, Pages: 1-10(2018)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2018.01.001
  CLC： R735.9
- Published Online：07 February 2018，
  
  Published：07 February 2018
- 稿件说明：
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张师容,靳　伟,刘　亮,等 . 2017年胰腺癌基础研究及诊疗新进展[J]. 中国癌症杂志, 2018, 28(1): 1-10.

张师容, 靳　伟, 刘　亮. Recent advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2017[J]. China Oncology, 2018, 28(1): 1-10.
张师容,靳　伟,刘　亮,等 . 2017年胰腺癌基础研究及诊疗新进展[J]. 中国癌症杂志, 2018, 28(1): 1-10. DOI： 10.19401/j.cnki.1007-3639.2018.01.001.

张师容, 靳　伟, 刘　亮. Recent advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2017[J]. China Oncology, 2018, 28(1): 1-10. DOI： 10.19401/j.cnki.1007-3639.2018.01.001.

摘要

胰腺癌是恶性程度极高的消化道肿瘤，疾病进展快，患者预后差，早期病情隐匿；同时手术切除率及化疗有效率低。近年来胰腺癌发病率逐年升高，成为危害人类健康的重大公共卫生问题。随着人们对胰腺癌生物学行为认识的不断加深，基础研究为临床治疗提供了理论依据，并丰富了临床治疗手段。胰腺癌的治疗模式已由单纯的外科治疗过渡到多学科综合诊治的模式。该文参考2017年胰腺癌研究领域发表的最新文献，对胰腺癌流行病学、发病因素、基础热点研究及临床研究新进展进行综述。

Abstract

Pancreatic cancer is a highly lethal disease in gastrointestinal malignant tumors. The prognosis of patients with pancreatic cancer is poor

due to the rapid progression

lack of early diagnosis

low surgical resection rate and inefficiency of chemotherapy. The incidence of pancreatic cancer has increased significantly in the recent years. As the understanding of tumor behavior deepens

the basic research navigates new routes for clinical treatment and enriches clinical methods. Pancreatic cancer treatment has been transitioned from “surgery first” to multidisciplinary collaborative treatment team (MDT) models. In this review

we summarized recent high quality studies on pancreatic cancer including epidemiological investigation

pathogenic factor

advances in basic research

and clinical treatment.

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Related Institution

Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University; Pancreatic Cancer Institute, Fudan University; Shanghai Pancreatic Cancer Institute

复旦大学附属肿瘤医院胰腺外科，复旦大学胰腺肿瘤研究所，上海市胰腺肿瘤研究所，复旦大学上海医学院肿瘤学系

复旦大学附属肿瘤医院胰腺外科、胰腺癌研究所，复旦大学上海医学院肿瘤学系

Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai Pancreatic Cancer Institute, Shanghai Key Laboratory of Precision Medicine for Pancreatic Cancer, Pancreatic Cancer Institute, Fudan University

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