The role of radiotherapy in nipple-areola complex-sparing mastectomy for patients with breast cancer

俞晓立; 郭小毛

doi:10.3969/j.issn.1007-3969.2016.05.004

您当前的位置：

首页 >

文章列表页 >

The role of radiotherapy in nipple-areola complex-sparing mastectomy for patients with breast cancer

更新时间：2025-12-31

- The role of radiotherapy in nipple-areola complex-sparing mastectomy for patients with breast cancer
- China Oncology Vol. 26, Issue 5, Pages: 378-382(2016)
- 作者机构：
  
  复旦大学附属肿瘤医院放射治疗中心，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1007-3969.2016.05.004
  CLC：
- Published Online：23 June 2016，
  
  Published：23 June 2016
- 稿件说明：
移动端阅览
俞晓立,郭小毛. 保留乳头乳晕复合体的乳腺癌切除术中放疗的地位探讨[J]. 中国癌症杂志, 2016, 26(5): 378-382.

俞晓立, 郭小毛. The role of radiotherapy in nipple-areola complex-sparing mastectomy for patients with breast cancer[J]. China Oncology, 2016, 26(5): 378-382.
俞晓立,郭小毛. 保留乳头乳晕复合体的乳腺癌切除术中放疗的地位探讨[J]. 中国癌症杂志, 2016, 26(5): 378-382. DOI： 10.3969/j.issn.1007-3969.2016.05.004.

俞晓立, 郭小毛. The role of radiotherapy in nipple-areola complex-sparing mastectomy for patients with breast cancer[J]. China Oncology, 2016, 26(5): 378-382. DOI： 10.3969/j.issn.1007-3969.2016.05.004.

摘要

在乳腺癌切除术的术式选择中，保留乳头乳晕复合体(nipple-areola complex，NAC)的乳房切除术(nipple-areola complex-sparing mastectomy，NSM)保留了皮肤和NAC，从而有利于后期的重建。目前在NSM治疗中，有几个关键问题尚未达成统一共识，包括NSM术中或术后是否加用或联合局部放疗，最终指向保留NAC后的肿瘤复发的安全性即术后局部复发率问题。有研究报道，不管是术后放疗还是术中放疗，联合NSM都能降低局部复发率，然而，对比联合放疗的研究和未放疗的研究，显示NSM后局部复发率相似，因此从整个NSM的治疗原则出发，患者的选择和手术质控是整个治疗的关键，对于不同复发风险的患者需要采取不同的联合放疗的方案。

Abstract

The technique of nipple-areola complex (NAC)-sparing mastectomy (NSM) facilitates the breast reconstruction due to preserving the skin and NAC of breast in the treatment of breast cancer. Key issues still remain controversial in NSM

in terms of the role of radiotherapy combined with NSM and sequence of radiotherapy and NSM

which arise from the consideration of the oncology safety. Some investigations addressed that post-NSM external beam irradiation and intra-operative radiotherapy (IORT) combined with NSM could reduce the local recurrence rate. Based on the appropriate patient selection and god quality of surgery

radiotherapy would be applied in different strategies of combination with NSM according to the risk of local recurrence of the cancer.

关键词

Keywords

references

Views

2018

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Value of global longitudinal strain in assessing radiation-induced heart disease in breast cancer: systematic review and meta-analysis

The clinicopathologic factors associated with nipple-areola complex involvement in breast cancer

Guidelines for breast cancer diagnosis and treatment by China Anti-Cancer Association (2026 edition)

Progress and prospects of CENPA-driven chromosomal instability in breast cancer: mechanisms, prognostic implications, and therapeutic perspectives

A study of 30-year trends in incidence and mortality risks of breast cancer among young women in China

Related Author

Xiaofei XU

Lixia ZHANG

Heyang DAI

Lingyun CHEN

Jiaojiao XUE

Qingxia LI

阮　淼

水若鸿

Related Institution

Graduate School, Hebei Medical University

Fourth Department of Oncology, Hebei General Hospital

Graduate School, North China University of Science and Technology

复旦大学附属肿瘤医院病理科，复旦大学上海医学院肿瘤学系

Department of Breast Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

AI问答

⁰