黄建琴, 朱芝玲. Analysis of 7 cases of fallopian tube carcinosarcoma and literature review[J]. China Oncology, 2016, 26(8): 693-698. DOI: 10.19401/j.cnki.1007-3639.2016.08.009.
Background and purpose: Fallopian tube carcinosarcoma is a rare malignant tumor that is prone to metastasis and recurrence. Patients with the malignancy often have poor prognosis. This paper retrospectively analyzed the clinical manifestation
pathology
treatment and prognosis of fallopian tube carcinosarcoma. Methods: The clinical manifestations
pathological features
treatment and survival time of 7 cases of fallopian tube carcinosarcoma were retrospectively analyzed. Results: The most common symptoms of 7 cases of fallopian tube carcinosarcoma were irregular vaginal bleeding (4/7
57.1%). Among 7 cases
one case was stage Ⅰa
1 stage Ⅱa
1 stage Ⅱb
1 stage Ⅲb
and 3 stage Ⅲc. Four cases (57.1%) were heterologous and found to have cartilage components whereas 3 cases (42.9%) were homologous. Seven cases were performed with tumor volume reduction surgery
and 6 cases with chemotherapy
while no one received radiotherapy. Five patients survived and 2 were dead. The survival time of 3 patients was more than 5 years. The longest survival time to the end of the follow-up was 114 months. Conclusion: The pathological examination is the diagnostic means of fallopian tube carcinosarcoma. The prognosis of the patients with the pathological characteristics of the homologous is better than that of the heterologous. Satisfactory reduction of tumor
postoperative chemotherapy with adequate TP regimen
combined with systemic chemotherapy and intraperitoneal chemotherapy may be an effective treatment for fallopian tube carcinosarcoma.