Long non-coding RNA (lncRNA) is a class of RNA molecules

transcripted by RNA polymerase Ⅱ

which consists of more than 200 nucleotides and protein-coding function. Many studies have indicated that lncRNA plays an important role in epigenetics

transcription and post-translational processing. The abnormal expression of lncRNA significantly correlates with occurence

development

and metastasis of renal cell carcinoma (RCC) and prognosis of the patients with RCC. This paper summarizes the advances in the research on lncRNA in RCC to reveal the mechanisms of the disease at the molecular level

in order to provide new methods of prevention

diagnosis

treatment and prognostic assessment of RCC.