袁 媛, 钱朝霞, 李文涛. CT guided cryoablation in local recurrence after radical resection of the rectal carcinoma[J]. China Oncology, 2017, 27(2): 140-144. DOI: 10.19401/j.cnki.1007-3639.2017.02.010.
Background and purpose: The local recurrence is one of the main causes of treatment failure for rectal carcinomas after radical resection. This study aimed to investigate the feasibility
safety
and efficacy of CT guided cryoablation in local recurrence after radical resection of rectal carcinomas. Methods: From Oct. 2013 to Jan. 2015
a total of 22 patients were enrolled in this study
and a follow-up of 12-32 months were performed. The image follow-up was by contrast-enhanced CT or MRI of pelvic. The technical success rate
complications and managements
and 1-year local control rate were recorded. The degree of pain between preablation and postablation was compared by scores of numerical rating scale (NRS). Results: The technical success rate was 100%. The main complication rate was 18.5%
including dysuresia
muscle strength decreased of affected side
abscess formation
severe frostbite. The 1-year local control rate was 72.7%
and the time to progression of local lesion were (11.1±4.3) months. Scores of NRS had significant difference between preablation and 3-day postablation
and preablation and 6-month postablation (P0.05). There was no significant difference between preablation and 12-month postablation (P=0.854). Conclusion: CT-guided cryoablation as a new method for local recurrence after radical resection of rectal carcinomas was safe and feasible