整合素&amp;#x003b2;3在肺腺癌骨转移中的作用及应用价值

穆佳倩; 滕小艳; 魏丽荣; 仇荣; 桂鹏程; 杜玉珍

doi:10.19401/j.cnki.1007-3639.2022.04.008

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整合素β3在肺腺癌骨转移中的作用及应用价值

论著选登 | 更新时间：2025-12-31

- 整合素β3在肺腺癌骨转移中的作用及应用价值
- The role and application value of integrin β3 in bone metastasis of lung adenocarcinoma
- 中国癌症杂志 2022年32卷第4期页码：351-356
- 作者机构：
  
  1. 上海海洋大学水产与生命学院,上海 201306
  2. 上海交通大学附属第六人民医院检验科,上海 201306
- 作者简介：
  
  [ "穆佳倩（ORCID：0000-0002-2158-782X）,硕士 E-mail: 1104959197@qq.com" ]
  杜玉珍（ORCID：0000-0002-3395-4471）,博士,主任技师,上海市第六人民医院检验科副主任 E-mail: yzdu@sjtu.edu.cn
- 基金信息：
  
  国家自然科学基金(81974315)
- DOI：10.19401/j.cnki.1007-3639.2022.04.008
  中图分类号： R734.2
- 收稿：2021-12-27，
  
  修回：2021-03-01，
  
  纸质出版：2022-04-30
- 稿件说明：
移动端阅览
穆佳倩, 滕小艳, 魏丽荣, 等. 整合素β3在肺腺癌骨转移中的作用及应用价值[J]. 中国癌症杂志, 2022,32(4):351-356.

Jiaqian MU, Xiaoyan TENG, Lirong WEI, et al. The role and application value of integrin β3 in bone metastasis of lung adenocarcinoma[J]. China Oncology, 2022, 32(4): 351-356.
穆佳倩, 滕小艳, 魏丽荣, 等. 整合素β3在肺腺癌骨转移中的作用及应用价值[J]. 中国癌症杂志, 2022,32(4):351-356. DOI： 10.19401/j.cnki.1007-3639.2022.04.008.

Jiaqian MU, Xiaoyan TENG, Lirong WEI, et al. The role and application value of integrin β3 in bone metastasis of lung adenocarcinoma[J]. China Oncology, 2022, 32(4): 351-356. DOI： 10.19401/j.cnki.1007-3639.2022.04.008.

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Abstract

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references

HIRSCH F R , SCAGLIOTTI G V , MULSHINE J L , et al . Lung cancer: current therapies and new targeted treatments [J ] . Lancet , 2017 , 389 ( 10066 ): 299 - 311 . DOI: 10.1016/S0140-6736(16)30958-8 http://doi.org/10.1016/S0140-6736(16)30958-8 https://linkinghub.elsevier.com/retrieve/pii/S0140673616309588 https://linkinghub.elsevier.com/retrieve/pii/S0140673616309588

SIEGEL R L , MILLER K D , JEMAL A . Cancer statistics, 2018 [J ] . CA A Cancer J Clin , 2018 , 68 ( 1 ): 7 - 30 . DOI: 10.3322/caac.21442 http://doi.org/10.3322/caac.21442 http://doi.wiley.com/10.3322/caac.21442 http://doi.wiley.com/10.3322/caac.21442

OLIVEIRA M B , MELLO F C , PASCHOAL M E M . The relationship between lung cancer histology and the clinicopathological characteristics of bone metastases [J ] . Lung Cancer , 2016 , 96 : 19 - 24 . DOI: 10.1016/j.lungcan.2016.03.014 http://doi.org/10.1016/j.lungcan.2016.03.014 https://linkinghub.elsevier.com/retrieve/pii/S0169500216302604 https://linkinghub.elsevier.com/retrieve/pii/S0169500216302604

LI S L , PENG Y , WEINHANDL E D , et al . Estimated number of prevalent cases of metastatic bone disease in the US adult population [J ] . Clin Epidemiol , 2012 , 4 : 87 - 93 .

DUNNE E M , FRASER I M , LIU M . Stereotactic body radiation therapy for lung, spine and oligometastatic disease: current evidence and future directions [J ] . Ann Transl Med , 2018 , 6 ( 14 ): 283 . DOI: 10.21037/atm.2018.06.40 http://doi.org/10.21037/atm.2018.06.40 http://atm.amegroups.com/article/view/20259/20157 http://atm.amegroups.com/article/view/20259/20157

HAMIDI H , IVASKA J . Every step of the way: integrins in cancer progression and metastasis [J ] . Nat Rev Cancer , 2018 , 18 ( 9 ): 533 - 548 . DOI: 10.1038/s41568-018-0038-z http://doi.org/10.1038/s41568-018-0038-z https://doi.org/10.1038/s41568-018-0038-z https://doi.org/10.1038/s41568-018-0038-z

DAS V , KALYAN G , HAZRA S , et al . Understanding the role of structural integrity and differential expression of integrin profiling to identify potential therapeutic targets in breast cancer [J ] . J Cell Physiol , 2018 , 233 ( 1 ): 168 - 185 . DOI: 10.1002/jcp.25821 http://doi.org/10.1002/jcp.25821 https://onlinelibrary.wiley.com/doi/10.1002/jcp.25821 https://onlinelibrary.wiley.com/doi/10.1002/jcp.25821

SWITALA-JELEN K , DABROWSKA K , OPOLSKI A , et al . The biological functions of beta3 integrins [J ] . Folia Biol (Praha ), 2004 , 50 ( 5 ): 143 - 152 .

ROBINSON S D , HODIVALA-DILKE K M . The role of β3-integrins in tumor angiogenesis: context is everything [J ] . Curr Opin Cell Biol , 2011 , 23 ( 5 ): 630 - 637 . DOI: 10.1016/j.ceb.2011.03.014 http://doi.org/10.1016/j.ceb.2011.03.014 https://linkinghub.elsevier.com/retrieve/pii/S0955067411000482 https://linkinghub.elsevier.com/retrieve/pii/S0955067411000482

WEILBAECHER K N , GUISE T A , MCCAULEY L K . Cancer to bone: a fatal attraction [J ] . Nat Rev Cancer , 2011 , 11 ( 6 ): 411 - 425 . DOI: 10.1038/nrc3055 http://doi.org/10.1038/nrc3055 https://doi.org/10.1038/nrc3055 https://doi.org/10.1038/nrc3055

CARTER R Z , MICOCCI K C , NATOLI A , et al . Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer [J ] . J Pathol , 2015 , 235 ( 5 ): 760 - 772 . DOI: 10.1002/path.4490 http://doi.org/10.1002/path.4490 https://onlinelibrary.wiley.com/doi/10.1002/path.4490 https://onlinelibrary.wiley.com/doi/10.1002/path.4490

GU H B , SUN L , DOU Z W , et al . Analysis of lung adenocarcinoma with bone metastasis: a case report [J ] . Transl Lung Cancer Res , 2020 , 9 ( 2 ): 389 - 392 . DOI: 10.21037/tlcr.2020.03.11 http://doi.org/10.21037/tlcr.2020.03.11 http://tlcr.amegroups.com/article/view/37898/html http://tlcr.amegroups.com/article/view/37898/html

北京医学奖励基金会肺癌青年专家委员会 , 中国胸外科肺癌联盟 . 肺癌骨转移诊疗专家共识(2019版) [J ] . 中国肺癌杂志 , 2019 , 22 ( 4 ): 187 - 207 .

The Youth Specialists Committee of Lung Cancer of Beijing Medical Award Foundaton , Chinese Lung Cancer Union . Expert consensus on the diagnosis and treatment of bone metastasis in lung cancer(2019 version) [J ] . Chin J Lung Cancer , 2019 , 22 ( 4 ): 187 - 207 .

ZHANG N , MA D N , WANG L , et al . Insufficient radiofrequency ablation treated hepatocellular carcinoma cells promote metastasis by up-regulation ITGB3 [J ] . J Cancer , 2017 , 8 ( 18 ): 3742 - 3754 . DOI: 10.7150/jca.20816 http://doi.org/10.7150/jca.20816 http://www.jcancer.org/v08p3742.htm http://www.jcancer.org/v08p3742.htm

BOULEFTOUR W , JUIGNET L , BOUET G , et al . The role of the SIBLING, bone sialoprotein in skeletal biology-contribution of mouse experimental genetics [J ] . Matrix Biol , 2016 , 52/53/54: 60 - 77 .

SLOAN E K , POULIOT N , STANLEY K L , et al . Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone [J ] . Breast Cancer Res , 2006 , 8 ( 2 ): R20 . DOI: 10.1186/bcr1398 http://doi.org/10.1186/bcr1398 http://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr1398 http://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr1398

BAKEWELL S J , NESTOR P , PRASAD S , et al . Platelet and osteoclast beta3 integrins are critical for bone metastasis [J ] . Proc Natl Acad Sci USA , 2003 , 100 ( 24 ): 14205 - 14210 . DOI: 10.1073/pnas.2234372100 http://doi.org/10.1073/pnas.2234372100 https://pnas.org/doi/full/10.1073/pnas.2234372100 https://pnas.org/doi/full/10.1073/pnas.2234372100

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整合素&#x003b2;3在肺腺癌骨转移中的作用及应用价值

The role and application value of integrin &#x003b2;3 in bone metastasis of lung adenocarcinoma

DOI：10.19401/j.cnki.1007-3639.2022.04.008

摘要

Abstract

关键词

Keywords

references

整合素β3在肺腺癌骨转移中的作用及应用价值

The role and application value of integrin β3 in bone metastasis of lung adenocarcinoma