LncRNA DLEU7-AS1通过调控膜突蛋白MSN的表达促进胃癌细胞增殖与迁移的作用机制

肖岚姝, 潘柳荻, 刘毅, 王洁, 陈惠

LncRNA DLEU7-AS1 contributes to proliferation and migration of gastric cancer by regulating MSN transcription

XIAO Lanshu, PAN Liudi, LIU Yi, WANG Jie, CHEN Hui

图10 DLEU7-AS1调控MSN的表达

Fig. 10 DLEU7-AS1 regulated MSN expression A: Volcano plot of differential genes by RNA-seq analysis of HGC-27 transfected with si-491 and si-NC; B: RTFQ-PCR analysis of MSN mRNA level after transfection of si-RNA and si-491 in AGS and HGC-27; C: RTFQ-PCR analysis of MSN mRNA level after DLEU7-AS1 overexpression in MGC-803 and SGC-7901; D: Western blot analysis of MSN protein expression level after transfection of si-RNA and si-491 in AGS and HGC-27. *: P<0.05, compared with si-NC/Con260; **: P<0.01, compared with si-NC/Con260; ***: P<0.001, compared with si-NC/Con260.