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间皮瘤组织病理学诊断临床实践指南(2025年版)
中国研究型医院学会病理学专业委员会, 上海市抗癌协会肿瘤病理专业委员会
Practice guideline for the histopathological diagnosis of mesothelioma (2025 version)
Expert Committee on Pathology of Chinese Research Hospital Association , Professional Committee on Tumor Pathology of Shanghai Anticancer Association

图4. 不同部位间皮瘤的标志物检测
A: 上皮样间皮瘤失表达BAP1;B: 肉瘤样间皮瘤弥漫表达GATA3;C: 肉瘤样间皮瘤弥漫表达PD-L1(22C3);D: FISH检测显示CDKN2Ap16)缺失;E: 原位间皮瘤,表面间皮细胞呈单层排列,显示轻度异型性;F: 原位间皮瘤,表面间皮细胞失表达BAP1。

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