孙向洁, 杨文涛. Issues on immunohistochemistry for molecular classification of breast cancer[J]. China Oncology, 2019, 29(3): 161-165. DOI: 10.19401/j.cnki.1007-3639.2019.03.001.
there are 4 intrinsic subtypes of breast cancer identified by gene expression profiling: luminal A
luminal B
human epidermal growth factor receptor 2 (HER2)-enriched and basal-like subtypes. As the application of gene expression profiling in daily practice is not practical
using immunohistochemistry as a surrogate for intrinsic subtypes are used worldwide. This review aimed to standardize and promote the immunohistochemistry for molecular classification of breast cancer.