中国癌症杂志 ›› 2021, Vol. 31 ›› Issue (1): 76-80.doi: 10.19401/j.cnki.1007-3639.2021.01.010

• 综述 • 上一篇    下一篇

肺癌相关异常脂代谢的研究进展

张翠翠,秦婷婷,孟昭婷 综述 ,李 凯 审校

  

  1. 天津医科大学肿瘤医院肺部肿瘤内科,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,
    天津市恶性肿瘤临床医学研究中心,天津市肺癌中心,天津 300060
  • 出版日期:2021-01-30 发布日期:2021-02-23
  • 通信作者: 李 凯 E-mail: likai_fnk@163.com

Research advances in abnormal lipid metabolism of lung cancer

ZHANG Cuicui, QIN Tingting, MENG Zhaoting, LI Kai#br#   

  1. Department of Thoracic Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin Lung Cancer Center, Tianjin 300060, China

  • Published:2021-01-30 Online:2021-02-23
  • Contact: LI Kai E-mail: likai_fnk@163.com

摘要: 在对肺癌发生、发展及治疗的研究中发现,其脂代谢与上述过程均有密切关系。分析脂代谢与肺癌的关系,可能有助于准确诊断肺癌、预测疗效及评估预后,并开发基于肿瘤脂代谢的治疗药物。对肺癌患者的血脂表现特点、与疗效的关系及可能影响脂代谢的药物进行了综述,以期为临床工作提供参考。

关键词: 肺癌, 脂代谢, 相关性

Abstract: Recent study has found that lipid metabolism has close relation to the occurrence, development and therapy of lung cancer and gradually becomes a hot topic in cancer cell metabolism. Analyzing the relationship between lipid metabolism and lung cancer may be helpful for accurate diagnosis, prediction of therapeutic efficacy and estimation of prognosis. Additionally, it is possible to develop drugs for tumor lipid metabolism. Therefore, this paper reviewed the characteristics of blood lipid in patients with lung cancer, their relationship to therapeutic efficacy and the medicines for lipid metabolism. This can provide reference for treatment targeting lipid metabolism in lung cancer.

Key words: Lung cancer, Lipid metabolism, Correlation