中国癌症杂志 ›› 2014, Vol. 24 ›› Issue (2): 81-86.doi: 10.3969/j.issn.1007-3969.2014.02.001

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胰腺癌淋巴转移诊治进展与处理规范

罗国培1,2,肖志文1,2,刘祖强1,2,郭萌1,2,龙江1,2,刘辰1,2,刘亮1,2,徐近1,2,倪泉兴1,2,虞先濬1,2   

  1. 1.复旦大学附属肿瘤医院胰腺肝胆外科,复旦大学上海医学院肿瘤学系,上海200032;
    2.中国抗癌协会胰腺癌专业委员会,上海 200032
  • 出版日期:2014-02-28 发布日期:2014-03-07
  • 通信作者: 虞先濬 E-mail:yuxianjun88@hotmail.com

Standard in the clinical management of the lymph metastasis in pancreatic cancer

LUO Guo-pei1,2,XIAO Zhi-wen1,2,LIU Zu-qiang1,2,GUO Meng1,2,LONG Jiang1,2,LIU Chen1,2,LIU Liang1,2,XU Jin1,2,NI Quan-xing1,2,YU Xian-jun1,2   

  1. Department of Pancreas and Hepatobiliary Surgery, Pancreas Cancer Institute, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University; China Anti-cancer Association Pancreatic Cancer Committee, Shanghai 200032, China
  • Published:2014-02-28 Online:2014-03-07
  • Contact: YU Xian-jun E-mail: yuxianjun88@hotmail.com

摘要:

淋巴转移是影响胰腺癌患者预后的最重要因素之一,能反映胰腺癌的生物学特性和侵袭潜能,而目前关于胰腺癌淋巴转移的临床诊治尚未达成统一。现就胰腺癌淋巴转移率及对预后的影响、胰腺癌淋巴转移规律、前哨淋巴结、术中淋巴结示踪、淋巴转移与胰腺癌TNM分期、区域淋巴结清扫、淋巴结检出个数、淋巴转移对术后辅助治疗的指导意义、淋巴导向治疗等进行阐述。

关键词: 胰腺癌, 淋巴转移, 诊治, 规范

Abstract:

Lymph metastasis has great impact on the prognosis of pancreatic cancer patients, which canreflect the biological and invasive potential of pancreatic cancer. However, currently, there is no standard in the clinical management of the lymph metastasis in pancreatic cancer. In this report, we will discuss and summarize the followings: lymph metastatic rate and its impact on prognosis, the rule of lymph metastasis, sentinel lymph node, intra-operative lymph nodes mapping, TNM staging, regional lymph nodes resection, number of lymph nodes examined, lymph node ratio, guiding adjuvant treatments, lymphatic targeted therapy.

Key words: Pancreatic cancer, Lymph metastasis, Diagnosis and treatment, Standard