中国癌症杂志 ›› 2020, Vol. 30 ›› Issue (12): 1031-1034.doi: 10.19401/j.cnki.1007-3639.2020.12.011

• 论著 • 上一篇    下一篇

千伏级锥形束CT与Catalyst TM 系统在影像引导放疗过程中的对比研究

吴子毅,王 焱,孟怡然,许 青   

  1. 复旦大学附属肿瘤医院放疗科,复旦大学上海医学院肿瘤学系,上海 200032
  • 出版日期:2020-12-30 发布日期:2021-01-08
  • 通信作者: 许 青 E-mail: qingxu68@hotmail.com

Comparison of the application of cone-beam CT and Catalyst TM system in image-guided radiotherapy

WU Ziyi, WANG Yan, MENG Yiran, XU Qing   

  1. Department of Radiation Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Published:2020-12-30 Online:2021-01-08
  • Contact: XU Qing E-mail: qingxu68@hotmail.com

摘要: 背景与目的:光学体表成像系统应用于图像引导的放疗过程。比较分析锥形束CT(cone-beam computed tomography,CBCT)和Catalyst TM 系统在患者放疗摆位误差检测方面的临床价值。方法:选取复旦大学附属肿瘤医院放射治疗中心的33例胸部肿瘤患者进行体位固定后,进行同次摆位的CBCT和Catalyst TM 系统图像采集。将采集图像和模拟定位图像进行配准对比,分别记录两种系统在xyz方向的平移误差值以及在头脚方向旋转(pitch,PIT)、左右方向旋转(roll,ROL)、水平方向旋转(rotation,RTN)3个方向的旋转误差值,计算其平均值、标准差、系统误差和随机误差,采用配对样本t检验比较数据差异有无统计学意义。结果:CBCT配准在平移方向上的摆位误差xyz方向的结果为(0.95±1.18)mm、(1.28±1.63)mm和(0.97±1.20)mm,在旋转方向上的摆位误差PIT、ROL、RTN结果为(0.73±0.65)°、(1.07±0.86)°和(0.69±0.69)°。Catalyst TM 系统配准在平移方向上的摆位误差xyz方向的结果为(0.96±1.35)mm、(1.43±1.66)mm和(1.59±1.98)mm,在旋转方向上的摆位误差PIT、ROL和RTN结果为(0.86±0.80)°、(0.87±0.74)°和(0.75±0.76)°。两系统之间的系统误差和随机误差的差值均<1 mm。结论:Catalyst TM 系统与CBCT系统检测患者放疗摆位误差差异无统计学意义,Catalyst TM 系统可代替CBCT系统进行放疗摆位误差的检测。

关键词: 锥形束CT, Catalyst TM 系统, 放射治疗, 摆位误差

Abstract:  Background and purpose: Optical surface imaging system is used in image-guided radiotherapy (IGRT). This study aimed to evaluate the clinical applicability of the Catalyst TM system and cone-beam computed tomography (CBCT) in tumor radiation therapy. Methods: Thirty-three patients with thorax tumor were fixed with suitable methods at Fudan University Shanghai Cancer Center. Catalyst TM system and CBCT acquired the same time images. The images were aligned with simulation planning CT images. These aligned results for images in x, y and z directions for translation error and pitch (PIT), roll (ROL) and rotation (RTN) directions for rotation error were obtained, and means, standard deviations, systemic error and random error were calculated. Paired samples t test was applied to evaluate the differences. Results: The setup errors of CBCT registration in x, y and z translational directions were (0.95±1.18) mm, (1.28±1.63) mm and (0.97±1.20) mm, respectively. The setup errors of CBCT registration in PIT, ROL and RTN rotational directions were (0.73±0.65)°, (1.07±0.86)° and (0.69±0.69)°, respectively. The setup errors of Catalyst TM registration in x, y and z translational directions were (0.96±1.35) mm, (1.43±1.66) mm and (1.59±1.98) mm, respectively. The setup errors of Catalyst TM registration in PIT, ROL and RTN rotational directions were (0.86±0.80)°, (0.87±0.74)° and (0.75±0.76)°, respectively. The differences in systemic error and random error between the two methods were less than 1 mm. Conclusion: There is no significant difference between the two approaches. Catalyst TM could be used as an alternative to CBCT.

Key words: Cone-beam computed tomography, Catalyst TM system, Radiation therapy, Setup errors