中国癌症杂志 ›› 2016, Vol. 26 ›› Issue (4): 346-350.doi: 10.3969/j.issn.1007-3969.2016.04.010

• 综述 • 上一篇    下一篇

放疗在乳腺癌骨转移中的临床应用进展

胡群超 综述 俞晓立,郭小毛 审校   

  1. 复旦大学附属肿瘤医院放疗科,复旦大学上海医学院肿瘤学系,上海 200032
  • 出版日期:2016-04-30 发布日期:2016-06-16
  • 通信作者: 郭小毛 E-mail:guoxiaomao188@outlook.com

Progress in the clinical use of radiotherapy for bone metastasis in breast cancer

HU Qunchao, YU Xiaoli, GUO Xiaomao   

  1. Department of Radiation Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Published:2016-04-30 Online:2016-06-16
  • Contact: GUO Xiaomao E-mail: guoxiaomao188@outlook.com

摘要: 骨转移是晚期乳腺癌最常见的远处转移,多伴有局部疼痛、肢体功能障碍等症状,常导致患者的生存质量下降。由骨转移引起的病理性骨折等骨相关事件(skeletal-related events,SREs)会显著增加乳腺癌患者的死亡风险。积极有效的骨转移治疗有重要的临床意义,放疗是重要的局部治疗手段。本文就放疗在乳腺癌骨转移中的临床应用进展进行综述,着重阐述放疗实施手段及综合治疗模式的循证医学证据。

关键词: 乳腺癌, 骨转移, 骨相关事件, 放疗, 综合治疗

Abstract: Bone remains the predominant site of metastasis in advanced breast cancer. Bone metastases dramatically decrease the quality of life. Moreover, pathologic fractures and other skeletal-related events (SREs) caused by bone metastases could result in higher mortality risk in patients with breast cancer. Palliative radiotherapy is a crucial element in bone metastases treatment. The present review discusses the emerging evidence in bone metastases of breast cancer, focusing on optimized radiotherapy strategies and multidisciplinary management.

Key words: Breast neoplasms, Bone metastasis, Skeletal-related events, Radiotherapy, Multidisciplinary management