Research progress on applications of nanomaterials in cancer theranostics

尹翼鹏晨; 张　琴; 傅小龙

doi:10.19401/j.cnki.1007-3639.2019.05.002

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Research progress on applications of nanomaterials in cancer theranostics

更新时间：2026-01-27

- Research progress on applications of nanomaterials in cancer theranostics
- China Oncology Vol. 29, Issue 5, Pages: 328-337(2019)
- 作者机构：
  
  上海交通大学附属胸科医院放疗科,上海,200030
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2019.05.002
  CLC： R730.5;TB383.1
- Published Online：03 June 2019，
  
  Published：03 June 2019
- 稿件说明：
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尹翼鹏晨，张　琴，傅小龙. 纳米材料在肿瘤诊疗中的应用研究进展[J]. 中国癌症杂志, 2019, 29(5): 328-337.

尹翼鹏晨, 张　琴, 傅小龙. Research progress on applications of nanomaterials in cancer theranostics[J]. China Oncology, 2019, 29(5): 328-337.
尹翼鹏晨，张　琴，傅小龙. 纳米材料在肿瘤诊疗中的应用研究进展[J]. 中国癌症杂志, 2019, 29(5): 328-337. DOI： 10.19401/j.cnki.1007-3639.2019.05.002.

尹翼鹏晨, 张　琴, 傅小龙. Research progress on applications of nanomaterials in cancer theranostics[J]. China Oncology, 2019, 29(5): 328-337. DOI： 10.19401/j.cnki.1007-3639.2019.05.002.

摘要

恶性肿瘤是目前影响人类健康的头号元凶。尽管肿瘤诊断与治疗的手段不断发展，但是由于肿瘤的异质性、隐匿性等原因，现有的肿瘤诊疗手段难以有效地克服肿瘤的复发、转移。近年来，随着纳米技术的不断发展，纳米材料因其良好的理化性质，如具有肿瘤靶向性、较好的生物相容性、易于功能化等，在肿瘤诊疗方面受到广泛关注，已有多项产品进入临床试验阶段或投入应用。对纳米材料在肿瘤诊断、化疗、放疗、光疗及免疫治疗等相关方面的应用研究进行了综述，并对其发展趋势予以了展望。

Abstract

Cancer is one of the leading causes of human death around the world. Despite of great advances in cancer diagnosis and treatment

also known as cancer theranostics

treatment responses

however

are often impeded by heterogeneity and stealthiness of cancer. Recently

with the fast development of nanotechnology

nanomaterials exhibit great potential in cancer theranostics for their excellent physiochemical properties including tumor targeting

good biocompatibility and easy functionalization. Moreover

a wide variety of nano-drugs have been tested in clinical trials

and some of them have been approved for human use. In this review

we aimed to provide insights into the applications of nanomaterials for innovative cancer diagnosis as well as enhanced chemotherapy

radiation therapy

phototherapy and immunotherapy of cancer. Additionally

we highlighted some examples and prospect for the further development of cancer nanotheranostics.

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