Stereotactic body radiation therapy in spinal oligometastases of breast cancer

俞晓立

doi:10.19401/j.cnki.1007-3639.2019.09.009

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Stereotactic body radiation therapy in spinal oligometastases of breast cancer

更新时间：2026-01-27

- Stereotactic body radiation therapy in spinal oligometastases of breast cancer
- China Oncology Vol. 29, Issue 9, Pages: 736-745(2019)
- 作者机构：
  
  复旦大学附属肿瘤医院放疗科，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2019.09.009
  CLC： R737.9;R730.55
- Published Online：20 November 2019，
  
  Published：20 November 2019
- 稿件说明：
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石薇, 俞晓立. 乳腺癌脊柱寡转移的体部立体定向放射治疗[J]. 中国癌症杂志, 2019, 29(9): 736-745.

俞晓立. Stereotactic body radiation therapy in spinal oligometastases of breast cancer[J]. China Oncology, 2019, 29(9): 736-745.
石薇, 俞晓立. 乳腺癌脊柱寡转移的体部立体定向放射治疗[J]. 中国癌症杂志, 2019, 29(9): 736-745. DOI： 10.19401/j.cnki.1007-3639.2019.09.009.

俞晓立. Stereotactic body radiation therapy in spinal oligometastases of breast cancer[J]. China Oncology, 2019, 29(9): 736-745. DOI： 10.19401/j.cnki.1007-3639.2019.09.009.

摘要

脊柱转移是乳腺癌最常见的远处转移部位。乳腺癌伴发的脊柱转移多以溶骨性改变为主，常导致骨相关事件（skeletal-related events，SRE）的发生，严重影响患者的生存质量。其中有一亚群的患者，肿瘤的转移潜能及总负荷有限，即处于所谓的“寡转移”状态。对于脊柱“寡转移”患者，放疗的作用不仅局限于姑息止痛，还是潜在根治的手段。将就体部立体定向放射治疗（stereotactic body radiation therapy，SBRT）在乳腺癌脊柱转移中的应用进行综述。

Abstract

Spine is the most common organ to be affected by metastatic breast cancer. Spinal metastases of breast cancer are mainly osteolytic and increase the risk of skeletal-related events (SRE)

which dramatically decrease the quality of life. Evidently

there is a subgroup of patients whose tumor is restricted in metastatic capacity and limited in total tumor burden

the so-called “oligometastatic” state. For patients with spinal oligometastases

radiotherapy is more than just palliative analgesic and could be potentially curative. This review detailed the application of stereotactic body radiation therapy (SBRT) in spinal metastases of breast cancer.

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