Advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2019

刘梦奇; 吉顺荣; 徐晓武; 虞先濬

doi:10.19401/j.cnki.1007-3639.2020.01.001

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Advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2019

更新时间：2026-01-27

- Advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2019
- China Oncology Vol. 30, Issue 1, Pages: 1-10(2020)
- 作者机构：
  
  复旦大学附属肿瘤医院胰腺外科，复旦大学胰腺肿瘤研究所，上海市胰腺肿瘤研究所，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2020.01.001
  CLC： R735.9
- Published Online：17 January 2020，
  
  Published：17 January 2020
- 稿件说明：
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刘梦奇, 吉顺荣, 徐晓武, 虞先濬. 2019年胰腺癌研究及诊疗新进展[J]. 中国癌症杂志, 2020, 30(1): 1-10.

刘梦奇, 吉顺荣, 徐晓武, et al. Advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2019[J]. China Oncology, 2020, 30(1): 1-10.
刘梦奇, 吉顺荣, 徐晓武, 虞先濬. 2019年胰腺癌研究及诊疗新进展[J]. 中国癌症杂志, 2020, 30(1): 1-10. DOI： 10.19401/j.cnki.1007-3639.2020.01.001.

刘梦奇, 吉顺荣, 徐晓武, et al. Advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2019[J]. China Oncology, 2020, 30(1): 1-10. DOI： 10.19401/j.cnki.1007-3639.2020.01.001.

摘要

胰腺癌是一种恶性程度极高的消化系统肿瘤，由于早期无明显症状、疾病进展快及化疗有效率低，患者预后极差，总体5年生存率只有约8%。近年来由于居民饮食习惯和生活方式的改变，胰腺癌的发病率逐年升高，严重威胁人民群众的生命健康。随着研究的不断深入，人们对胰腺癌生物学行为的认识及临床诊疗水平不断提高，胰腺癌的治疗模式也已由既往单纯的外科或内科治疗过渡到以多学科讨论为基础的综合治疗模式。本文参考2019年发表的胰腺癌相关研究报道，就胰腺癌发病因素、基础及临床研究新进展等方面进行综述。

Abstract

Pancreatic cancer is a highly malignant tumor of the digestive system. Due to the lack of early diagnosis

rapid disease progression and unsatisfactory chemotherapy effectiveness

the prognosis of patient is extremely poor with an overall 5-year survival rate of 8%. In recent years

with the changes in residents’ dietary habits and lifestyles

the incidence of pancreatic cancer has increased year by year

which seriously threatens the health of the people. With continuous research and efforts

our understanding of the biological behavior and clinical diagnosis and treatment of pancreatic cancer have been continuously improved. The treatment mode of pancreatic cancer has also transitioned from the purely surgical or chemical treatment in the past to a comprehensive treatment model based on multiple disciplinary teams. Here we reviewed the latest high quality studies published in 2019

and summarized the progress of pathogenesis

basic and clinical research on pancreatic cancer to provide theoretical support for conquering this lethal disease.

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Related Institution

Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

Department of Urology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University; Pancreatic Cancer Institute, Fudan University; Shanghai Pancreatic Cancer Institute

复旦大学附属肿瘤医院胰腺外科、胰腺癌研究所，复旦大学上海医学院肿瘤学系

Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai Pancreatic Cancer Institute, Shanghai Key Laboratory of Precision Medicine for Pancreatic Cancer, Pancreatic Cancer Institute, Fudan University

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