Cancer is one of the diseases that seriously harm human health. The cancer-related incidence and deaths are still increasing worldwide

which has brought heavy burden to the global public health system. During the long anticancer history

a variety of methods to treat tumors have been developed. More than 100 years ago

shortly after the discovery of Roentgen rays

people began to treat tumors with radiation

and thus pioneered radiation oncology. As a brachytherapy method

implantation of radioactive seeds acts well

has received public recognition

and becomes an important member of the oncology therapeutic spectrum. In vivo

some seeds can migrate from initial site of i

mplantation to other locations. Permanent interstitial brachytherapy and the incidence

mechanism

influence and prevention of 

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I seed migration were reviewed here.