Current status and prospect of perioperative treatment of stage Ⅲ melanoma

Yu XU; Yong CHEN; Jilong YANG; Guannan ZHU

doi:10.19401/j.cnki.1007-3639.2022.12.001

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Current status and prospect of perioperative treatment of stage Ⅲ melanoma

Specialists' Commentary | 更新时间：2025-12-31

- Current status and prospect of perioperative treatment of stage Ⅲ melanoma
- China Oncology Vol. 32, Issue 12, Pages: 1133-1146(2022)
- 作者机构：
  
  1. 复旦大学附属肿瘤医院骨软组织外科，复旦大学上海医学院肿瘤学系，上海 200032
  2. 天津医科大学肿瘤医院骨与软组织肿瘤科，国家恶性肿瘤临床医学研究中心，天津 300060
  3. 天津市恶性肿瘤临床医学研究中心，天津市肿瘤防治重点实验室，天津市肿瘤分子流行病重点实验室，天津 300060
  4. 空军军医大学（第四军医大学）西京皮肤医院，陕西西安 710032
- 作者简介：
- 基金信息：
  
  General Program of the National Natural Science Foundation of China(82272857)
- DOI：10.19401/j.cnki.1007-3639.2022.12.001
  CLC： R739.5
- Received：22 November 2022，
  
  Revised：2022-12-27，
  
  Published：30 December 2022
- 稿件说明：
移动端阅览
Yu XU, Yong CHEN, Jilong YANG, et al. Current status and prospect of perioperative treatment of stage Ⅲ melanoma[J]. China Oncology, 2022, 32(12): 1133-1146.
DOI：

Yu XU, Yong CHEN, Jilong YANG, et al. Current status and prospect of perioperative treatment of stage Ⅲ melanoma[J]. China Oncology, 2022, 32(12): 1133-1146. DOI： 10.19401/j.cnki.1007-3639.2022.12.001.

摘要

黑色素瘤是一种恶性程度极高的肿瘤，早期黑色素瘤经手术切除多可治愈，但对于高危型病例（ⅡB~Ⅳ期），辅助治疗是延长患者生命、改善预后的重要手段。近年来随着系统治疗药物的蓬勃发展，对于Ⅲ期可切除病例的围手术期治疗理念不断发生变化。本文着眼于外科手术规范及对预后的影响、术后辅助治疗选择、新辅助治疗的进展等热点问题进行梳理，并结合来源于中国患者的治疗数据进行分析讨论，希望为中国Ⅲ期黑色素瘤的围手术期治疗选择提供新的思路。

Abstract

Melanoma is one of the most dangerous tumors due to its high-grade malignancy. Though patients in early stage can be completely cured by surgery

for high-risk cases (stage ⅡB-Ⅳ)

adjuvant therapy is of great importance to prolong the survival and improve the prognosis. In recent years

thanks to the booming development of systemic regimen

the perioperative managements for stage Ⅲ cases have been continuously evolving. In the current paper

we focused on the role of lymph node biopsy and surgical resection

postoperative adjuvant therapy options

as well as the cutting-edge neoadjuvant therapy development

aiming to provide new perioperative strategies for stage Ⅲ melanoma patients.

关键词

Keywords

references

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