Advances in fundamental and translational breast cancer research in 2022

Ziyu WANG; Yi XIAO; Yizhou JIANG; Zhimin SHAO

doi:10.19401/j.cnki.1007-3639.2023.02.001

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Advances in fundamental and translational breast cancer research in 2022

Specialists' Commentary | 更新时间：2025-12-31

- Advances in fundamental and translational breast cancer research in 2022
- China Oncology Vol. 33, Issue 2, Pages: 95-102(2023)
- 作者机构：
  
  复旦大学附属肿瘤医院乳腺外科/复旦大学乳腺癌研究所，复旦大学上海医学院肿瘤学系，上海 200032
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2023.02.001
  CLC： R737.9
- Received：08 January 2023，
  
  Revised：2023-01-24，
  
  Published：28 February 2023
- 稿件说明：
移动端阅览
Ziyu WANG, Yi XIAO, Yizhou JIANG, et al. Advances in fundamental and translational breast cancer research in 2022[J]. China Oncology, 2023, 33(2): 95-102.
DOI：

Ziyu WANG, Yi XIAO, Yizhou JIANG, et al. Advances in fundamental and translational breast cancer research in 2022[J]. China Oncology, 2023, 33(2): 95-102. DOI： 10.19401/j.cnki.1007-3639.2023.02.001.

摘要

世界卫生组织（World Health Organization，WHO）国际癌症研究机构发布的数据显示，乳腺癌现已成为全球女性发病率最高的恶性肿瘤，严重威胁女性健康。2022年乳腺癌基础与转化研究领域进展颇丰，深化了对乳腺癌分子本质的认识，为乳腺癌精准治疗提供了新的思路。本文从肿瘤代谢、肿瘤微环境、微生物与肿瘤、肿瘤转移、肿瘤耐药与药物筛选、多组学研究、人工智能共7个方面对2022年乳腺癌基础与转化研究的年度进展进行总结，并对乳腺癌研究未来的发展方向进行展望，以期为乳腺癌研究的进一步深化提供参考。

Abstract

According to the data released by the International Cancer Research Institute of the World Health Organization (WHO)

breast cancer is the malignant tumor with the highest incidence rate in women

and seriously endangers women's health.Many impressive advances have been achieved in fundamental and translational research of breast cancer

which deepened the understanding of the molecular nature of breast cancer and provided new scientific strategies for the precision treatment of breast cancer. This paper summarized the annual advances in fundamental and translational breast cancer research in 2022 in seven sections: tumor metabolism

tumor microenvironment

microbes and tumors

tumor metastasis

tumor drug resistance and drug screening

multi-omics research and artificial intelligence. Furthermore

we proposed an outlook on the future directions of breast cancer research to provide a reference for future studies.

关键词

Keywords

references

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