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Risk of cancer therapy-related cardiotoxicity following the use of PD-1/PD-L1 inhibitors combined with chemoradiotherapy compared with chemoradiotherapy in solid tumors: a systematic review and Meta-analysis
Review | 更新时间：2026-02-09

    • Risk of cancer therapy-related cardiotoxicity following the use of PD-1/PD-L1 inhibitors combined with chemoradiotherapy compared with chemoradiotherapy in solid tumors: a systematic review and Meta-analysis

    • “The latest research focuses on the field of tumor treatment, and experts have found through meta-analysis that the combination of PD-1/PD-L1 inhibitors with radiotherapy and chemotherapy increases the risk of cardiac toxicity, especially in terms of heart failure and arrhythmia, providing important references for the safety evaluation of tumor treatment.”
    • China Oncology   Vol. 35, Issue 12, Pages: 1126-1139(2025)

    • DOI：10.19401/j.cnki.1007-3639.2025.12.005    

      CLC： R730.51

    • Received：09 September 2025，

      Revised：2025-12-01，

      Published：30 December 2025

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  • ZHENG Jinmei, WU Wanghui, ZHENG Jimei, et al. Risk of cancer therapy-related cardiotoxicity following the use of PD-1/PD-L1 inhibitors combined with chemoradiotherapy compared with chemoradiotherapy in solid tumors: a systematic review and Meta-analysis[J]. China Oncology, 2025, 35(12): 1126-1139. DOI： 10.19401/j.cnki.1007-3639.2025.12.005.

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