吴杲, 魏大中, 解明然, et al. The surgical safety analysis of elderly patients with thoracic esophageal squamous cell carcinoma[J]. China Oncology, 2014, 24(2): 151-154.
吴杲, 魏大中, 解明然, et al. The surgical safety analysis of elderly patients with thoracic esophageal squamous cell carcinoma[J]. China Oncology, 2014, 24(2): 151-154. DOI: 10.3969/j.issn.1007-3969.2014.02.012.
The surgical safety analysis of elderly patients with thoracic esophageal squamous cell carcinoma
背景与目的:老年食管癌发病率呈上升趋势。本研究旨在比较高龄老人和年轻老人两组胸段食管鳞癌患者临床病理资料、手术及术后情况,分析不同手术入路对高龄老年患者的影响。方法:回顾性分析2006年1月—2008年12月安徽医科大学附属省立医院胸外科收治的胸段食管鳞癌老年患者(60岁以上)371例。其中≥75岁的高龄老人53例,60~74岁的年轻老人318例,分别比较两组患者临床病理特征、手术情况、并发症及术后院内死亡率和平均住院时间,同时根据手术入路不同分为左进胸入路与右进胸入路,比较手术时间、术中出血量及术后并发症发生率等情况。结果:高龄老人组与年轻老人组相比术前合并症更多,术前ASA分级更高,术后并发症、住院时间及院内死亡率均明显增高,高龄老人组左胸入路较右胸入路术后并发症特别是肺部并发症更少(13.0% vs 40.0%),差异有统计学意义(P0.05)。结论:≥75岁的老年胸段食管鳞癌患者手术风险较大,可以通过选择相对简单的手术方式,减少术后并发症特别是肺部并发症的发生率。
Abstract
Background and purpose: The incidence rate of elderly esophageal carcinoma patients is increasing year by year. In this study
the clinicopathologic factors
operational factors and postoperative complications were compared between the older and the younger elderly patients with thoracic esophageal squamous cell carcinoma (ESCC)
and the influence of different surgical approaches to older elderly patients were analyzed. Methods: A retrospective review of 371 cases of elderly patients with thoracic esophageal squamous cell carcinoma (≥60 years) between Jan. 2006 and Dec. 2008 were performed. The patients were divided into two age groups. The patients over 75 years old named the older elderly group including 53 patients
and the patients between 60-74 years named the younger elderly group including 318 patients
the clinicopathological factors
operational factors
postoperative hospital mortality and average length of stay were compared. Meanwhile
according to different surgical approaches
the comparison of the left chest and right chest approach of operative time
blood loss and postoperative complication rate
and so on and so forth. Results: The older elderly group compared with the younger elderly group had more preoperative complications. Preoperative ASA classification and postoperative complications
length of stay and hospital mortality rates were significantly higher. The older elderly group over the right chest approach had less postoperative complications
especially pulmonary complications
the results were statistically significant.(13.0% vs 40.0%,P0.05) Conclusion: The patients over 75 years old with thoracic esophageal squamous cell carcinoma have a higher risk during the operation
we can choose relatively simpler operation approach to reduce the incidence of postoperative complications
Influencing factors of cardiovascular adverse events risk in elderly patients with esophageal cancer undergoing video-assisted thoracoscopic surgery and nomogram prediction model construction
Exploring innovative models of surgical treatment for rectal cancer
The value of surgery in the patients with de novo stage Ⅳ breast cancer
Prognostic factor analysis of surgical treatment for cerebellar metastases in 36 patients
A study on correlation of acetyltransferase KAT3b and ABCE1 acetylation in esophageal cancer
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Department of General Thoracic Surgery, The First Hospital of Danjiangkou City
Department of Anesthesiology, The First Hospital of Danjiangkou City
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Department of Neurosurgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University