Multiple myeloma: from diagnosis to staging

杨蕊雪; 高露; 施菊妹

doi:10.3969/j.issn.1007-3969.2014.10.002

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Multiple myeloma: from diagnosis to staging

更新时间：2025-12-31

- Multiple myeloma: from diagnosis to staging
- China Oncology Vol. 24, Issue 10, Pages: 727-731(2014)
- 作者机构：
  
  同济大学附属第十人民医院血液科,上海,200072
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1007-3969.2014.10.002
  CLC：
- Published Online：12 November 2014，
  
  Published：12 November 2014
- 稿件说明：
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杨蕊雪,高露,施菊妹. 多发性骨髓瘤的诊断进展与分期[J]. 中国癌症杂志, 2014, 24(10): 727-731.

杨蕊雪, 高露, 施菊妹. Multiple myeloma: from diagnosis to staging[J]. China Oncology, 2014, 24(10): 727-731.
杨蕊雪,高露,施菊妹. 多发性骨髓瘤的诊断进展与分期[J]. 中国癌症杂志, 2014, 24(10): 727-731. DOI： 10.3969/j.issn.1007-3969.2014.10.002.

杨蕊雪, 高露, 施菊妹. Multiple myeloma: from diagnosis to staging[J]. China Oncology, 2014, 24(10): 727-731. DOI： 10.3969/j.issn.1007-3969.2014.10.002.

摘要

多发性骨髓瘤(multiple myeloma，MM)是一种浆细胞恶性肿瘤，随着研究的深入，对MM的诊断不再局限于骨髓活检与影像学检查，而是向血清游离轻链、细胞遗传学和分子生物学检测方向发展，这使医务人员对该疾病的发生机制有了更深的了解，同时为预后评估提供了重要依据。下面主要从MM的实验室检查、诊断标准和分期3个方面对近年MM的诊断及其进展进行综述。

Abstract

Multiple myeloma (MM) is a plasma cell malignancy. With the development of the understanding of MM

the diagnosis is no more limited to bone marrow biopsy and imageological examination. Serum free light chain

cytogenetic analysis and molecular biology study are becoming increasingly widely used

which give us a deeper understanding of the mechanisms of MM and provide us with a clearer prognosis evaluation. Here is to make a review of the diagnosis and its development of MM from laboratory examination

diagnosis criteria and classification.

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