Update on the molecular targeted therapy for cervical cancer

杨莉; 程玺

doi:10.3969/j.issn.1007-3969.2015.01.013

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Update on the molecular targeted therapy for cervical cancer

更新时间：2025-12-31

- Update on the molecular targeted therapy for cervical cancer
- China Oncology Vol. 25, Issue 1, Pages: 73-80(2015)
- 作者机构：
  
  复旦大学附属肿瘤医院妇瘤科，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1007-3969.2015.01.013
  CLC：
- Published Online：08 May 2015，
  
  Published：08 May 2015
- 稿件说明：
移动端阅览
杨莉,程玺 . 宫颈癌分子靶向治疗的研究进展[J]. 中国癌症杂志, 2015, 25(1): 73-80.

杨莉, 程玺. Update on the molecular targeted therapy for cervical cancer[J]. China Oncology, 2015, 25(1): 73-80.
杨莉,程玺 . 宫颈癌分子靶向治疗的研究进展[J]. 中国癌症杂志, 2015, 25(1): 73-80. DOI： 10.3969/j.issn.1007-3969.2015.01.013.

杨莉, 程玺. Update on the molecular targeted therapy for cervical cancer[J]. China Oncology, 2015, 25(1): 73-80. DOI： 10.3969/j.issn.1007-3969.2015.01.013.

摘要

宫颈癌是世界范围内女性常见、死亡率高的恶性肿瘤。尽管其手术及放化疗治疗日趋成熟，但对晚期或转移性宫颈癌尚无满意的治疗手段。分子靶向治疗的进展为这类患者的治疗提供了新的思路。本文就针对血管内皮细胞生长因子通路、表皮生长因子受体、哺乳动物雷帕霉素靶蛋白、组蛋白去乙酰化酶、环氧化酶-2等的分子靶向类药物在宫颈癌治疗中的最新进展作一综述。

Abstract

Cervical cancer is one of the most common and deadliest cancers in females worldwide. Despite the treatment methods of surgery

radiotherapy and chemotherapy are maturing

the prognosis of patients with recurrent

advanced or metastatic cervical cancer remains poor. Molecular targeted therapy provides new hope for these patients. This review focuses on the advances in agents targeting vascular endothelial growth factor pathway

epidermal growth factor receptor

mammalian target of rapamycin

histone deacetylases and cyclooxygenase-2 in cervical cancer.

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Department of Pharmacy, Minhang Branch, Fudan University Shanghai Cancer Center

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