Research progress on circulating tumor cells and their detection in colorectal cancer

孙文洁; 章　真

doi:10.3969/j.issn.1007-3969.2015.11.003

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Research progress on circulating tumor cells and their detection in colorectal cancer

更新时间：2025-12-31

- Research progress on circulating tumor cells and their detection in colorectal cancer
- China Oncology Vol. 25, Issue 11, Pages: 854-860(2015)
- 作者机构：
  
  复旦大学附属肿瘤医院放疗科，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1007-3969.2015.11.003
  CLC：
- Published Online：01 February 2016，
  
  Published：01 February 2015
- 稿件说明：
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孙文洁,章　真. 结直肠癌患者外周血循环肿瘤细胞的检测及临床研究进展[J]. 中国癌症杂志, 2015, 25(11): 854-860.

孙文洁, 章　真. Research progress on circulating tumor cells and their detection in colorectal cancer[J]. China Oncology, 2015, 25(11): 854-860.
孙文洁,章　真. 结直肠癌患者外周血循环肿瘤细胞的检测及临床研究进展[J]. 中国癌症杂志, 2015, 25(11): 854-860. DOI： 10.3969/j.issn.1007-3969.2015.11.003.

孙文洁, 章　真. Research progress on circulating tumor cells and their detection in colorectal cancer[J]. China Oncology, 2015, 25(11): 854-860. DOI： 10.3969/j.issn.1007-3969.2015.11.003.

摘要

结直肠癌是最常见的恶性肿瘤之一，虽然综合治疗的开展使其疗效有较大改善，但仍有较多患者死于术后的复发和转移。循环肿瘤细胞(circulating tumor cell，CTC)来源于肿瘤组织，与肿瘤转移及预后密切相关。对CTC检测方法及其在结直肠癌中的临床研究进行综述。

Abstract

Colorectal cancer is one of the most common malignant tumors. Though the development of multidisciplinary therapy has largely improved the therapy effects

many patients still died of local recurrence and metastases after surgery. Circulating tumor cell (CTC) originates from primary tumor tissues and has a close relationship with cancer metastases and prognosis. This review summarizes the CTC detection methods and relevant clinical research on CTC in recent years.

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