Progress in the clinical use of radiotherapy for bone metastasis in breast cancer

胡群超; 俞晓立; 郭小毛

doi:10.3969/j.issn.1007-3969.2016.04.010

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Progress in the clinical use of radiotherapy for bone metastasis in breast cancer

更新时间：2025-12-31

- Progress in the clinical use of radiotherapy for bone metastasis in breast cancer
- China Oncology Vol. 26, Issue 4, Pages: 346-350(2016)
- 作者机构：
  
  复旦大学附属肿瘤医院放疗科，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1007-3969.2016.04.010
  CLC：
- Published Online：16 June 2016，
  
  Published：16 June 2016
- 稿件说明：
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胡群超,俞晓立,郭小毛. 放疗在乳腺癌骨转移中的临床应用进展[J]. 中国癌症杂志, 2016, 26(4): 346-350.

胡群超, 俞晓立, 郭小毛. Progress in the clinical use of radiotherapy for bone metastasis in breast cancer[J]. China Oncology, 2016, 26(4): 346-350.
胡群超,俞晓立,郭小毛. 放疗在乳腺癌骨转移中的临床应用进展[J]. 中国癌症杂志, 2016, 26(4): 346-350. DOI： 10.3969/j.issn.1007-3969.2016.04.010.

胡群超, 俞晓立, 郭小毛. Progress in the clinical use of radiotherapy for bone metastasis in breast cancer[J]. China Oncology, 2016, 26(4): 346-350. DOI： 10.3969/j.issn.1007-3969.2016.04.010.

摘要

骨转移是晚期乳腺癌最常见的远处转移，多伴有局部疼痛、肢体功能障碍等症状，常导致患者的生存质量下降。由骨转移引起的病理性骨折等骨相关事件(skeletal-related events，SREs)会显著增加乳腺癌患者的死亡风险。积极有效的骨转移治疗有重要的临床意义，放疗是重要的局部治疗手段。本文就放疗在乳腺癌骨转移中的临床应用进展进行综述，着重阐述放疗实施手段及综合治疗模式的循证医学证据。

Abstract

Bone remains the predominant site of metastasis in advanced breast cancer. Bone metastases dramatically decrease the quality of life. Moreover

pathologic fractures and other skeletal-related events (SREs) caused by bone metastases could result in higher mortality risk in patients with breast cancer. Palliative radiotherapy is a crucial element in bone metastases treatment. The present review discusses the emerging evidence in bone metastases of breast cancer

focusing on optimized radiotherapy strategies and multidisciplinary management.

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