林岩松. The clinical significance of thyroglobulin antibody measurement in 131I therapy of differentiated thyroid carcinoma[J]. China Oncology, 2019, 29(6): 452-456.
林岩松. The clinical significance of thyroglobulin antibody measurement in 131I therapy of differentiated thyroid carcinoma[J]. China Oncology, 2019, 29(6): 452-456. DOI: 10.19401/j.cnki.1007-3639.2019.06.009.
Serum thyroglobulin (Tg) is a major tumor marker for follow-up after treatment of patients with differentiated thyroid carcinoma (DTC). However
the accuracy of Tg measurement is interfered by thyroglobulin antibody (TgAb)
limiting the predictive value of Tg. Therefore
the follow-up of DTCs with positive TgAb remains a clinical puzzlement. Some researchers have proposed that TgAb could also serve as a surrogate tumor marker for the monitoring of DTC
but it remains controversial over the relationship between TgAb and disease status or prognosis after treatment. This article reviewed the clinical significance of TgAb measurement i
n
131
I therapy of DTC
in order to provide more evidence for clinical decision making in patients with positive TgAb.