马小开, 黄建康, 博, et al. Clinical characteristics of papillary thyroid microcarcinoma and risk factors for cervical lymph node metastasis: a clinical analysis of 228 cases[J]. China Oncology, 2019, 29(8): 590-594.
马小开, 黄建康, 博, et al. Clinical characteristics of papillary thyroid microcarcinoma and risk factors for cervical lymph node metastasis: a clinical analysis of 228 cases[J]. China Oncology, 2019, 29(8): 590-594. DOI: 10.19401/j.cnki.1007-3639.2019.08.005.
Background and purpose: The incidence of papillary thyroid microcarcinoma (PTMC) is increasing
and the overall prognosis is good. However
there is controversy in clinical diagnosis and treatment of the disease. In this study
we summarized the clinical characteristics and risk factors of PTMC by analyzing the data of patients in order to guide clinical precision treatment. Methods: We performed retrospective analysis of clinical and pathological data of patients with PTMC who underwent surgery from Jan. 2015 to Dec. 2017 in the First Affiliated Hospital of Bengbu Medical College. Results: Of the 228 patients
109 had central lymph node and/or lateral cervical lymph node metastasis (47.81%). Univariate analysis showed that gender
age
maximum tumor diameter and number of primary tumors were associated with cervical lymph node metastasis (all P value 0.05 ). Multivariate logistic analysis showed that male patient
less than 45 years of age
tumor maximum diameter ˃4 mm and multi-center lesion were independent risk factors for cervical lymph node metastasis of PTMC (all P value 0.05 ). Conclusion: Although PTMC is small
it does not indicate lower risk of lymph node metastasis
particularly patient who is male
younger than 45 years
whose tumor maximum diameter ˃4 mm or who has multi-center lesion should be actively involved in surgical intervention.