YANG Yunsong, JIANG Yizhou, HU Xin, et al. Research progress of breast tumor microenvironment-targeted therapy[J]. China Oncology, 2019, 29(12): 977-984.
YANG Yunsong, JIANG Yizhou, HU Xin, et al. Research progress of breast tumor microenvironment-targeted therapy[J]. China Oncology, 2019, 29(12): 977-984. DOI: 10.19401/j.cnki.1007-3639.2019.12.010.
Tumor microenvironment is composed of immune cells
fibroblasts and endothelial cells
and proliferation
invasion and metastasis of tumor cells are regulated by tumor microenvironment. Therefore
targeting both tumor cells and the surrounding microenvironment should be included in the comprehensive treatment of breast cancer. In this review
we summarized the prognostic value of the tumor microenvironment in breast cancer and how to increase the therapeutic effect of anti-cancer therapy through addition of anti-microenvironment therapy.