Ovarian cancer is one of the major health- and life-threatening diseases among females. In recent years
poly (ADP-ribose) polymerase inhibitors (PARPi)
as novel molecular-targeted therapy agents that bring benefits to ovarian cancer patients
have been recommended as maintenance therapy for platinum-sensitive recurrent ovarian cancer patients and postoperative maintenance therapy by several clinical guidelines. However
the safety issues
especially the hematological toxicities of the drugs
should be carefully regarded. This review compared the pharmacological characteristics and hematological toxicities of three different PARPi
so as to provide more information of the clinical application for the recurrent ovarian cancer patients.