潘星昊, 刘明斌, 张晓燕, et al. Advances in research of exosomes as targeted therapeutic vectors[J]. China Oncology, 2020, 30(9): 701-706. DOI: 10.19401/j.cnki.1007-3639.2020.09.010.
Exosomes are nanoscale vesicles derived from the inner membrane of cells
containing life information such as nucleic acids
proteins and lipids. They play an important role in life activities as a mechanism of intercellular communication. Compared to liposome carriers
exosomes are more stable
biocompatible and less immunogenic
and can penetrate biological barriers such as the blood-brain barrier and the placental barrier. This article focused on the basis of exosome vector targeting
the method of carrier loading and the current application progress and prospects.