中国抗癌协会多原发和不明原发肿瘤诊治指南（2023年版）

中国抗癌协会多原发和不明原发肿瘤专业委员会

doi:10.19401/j.cnki.1007-3639.2023.04.011

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中国抗癌协会多原发和不明原发肿瘤诊治指南（2023年版）

指南与共识 | 更新时间：2025-12-31

- 中国抗癌协会多原发和不明原发肿瘤诊治指南（2023年版）
- China Anti-Cancer Association guideline for diagnosis and treatment of cancer of multiple and unknown primaries (2023 edition)
- 中国癌症杂志 2023年33卷第4期页码：403-422
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.19401/j.cnki.1007-3639.2023.04.011
  中图分类号： R730
- 收稿：2023-02-13，
  
  修回：2023-04-07，
  
  纸质出版：2023-04-30
- 稿件说明：
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中国抗癌协会多原发和不明原发肿瘤专业委员会. 中国抗癌协会多原发和不明原发肿瘤诊治指南（2023年版）[J]. 中国癌症杂志, 2023,33(4):403-422.

Society of Cancer of Multiple and Unknown Primary of China Anti-Cancer Association Yuguang. China Anti-Cancer Association guideline for diagnosis and treatment of cancer of multiple and unknown primaries (2023 edition)[J]. China Oncology, 2023, 33(4): 403-422.
中国抗癌协会多原发和不明原发肿瘤专业委员会. 中国抗癌协会多原发和不明原发肿瘤诊治指南（2023年版）[J]. 中国癌症杂志, 2023,33(4):403-422. DOI： 10.19401/j.cnki.1007-3639.2023.04.011.

Society of Cancer of Multiple and Unknown Primary of China Anti-Cancer Association Yuguang. China Anti-Cancer Association guideline for diagnosis and treatment of cancer of multiple and unknown primaries (2023 edition)[J]. China Oncology, 2023, 33(4): 403-422. DOI： 10.19401/j.cnki.1007-3639.2023.04.011.

摘要

原发灶不明肿瘤（cancer of unknown primary，CUP）和多原发肿瘤（cancer of multiple primaries，CMP），因其临床异质性高、发病率低、循证医学证据的相对匮乏及临床疾病认识的相对局限，目前诊疗仍面临巨大挑战。随着对疾病影像学、病理学、基因特点等认识的不断深入，多学科的协作和发展，以及分子靶向治疗和免疫治疗的针对性探索正在不断地更新对这部分患者治疗的理念和手段。本指南的制定旨在为临床工作者提供CUP和CMP患者诊疗的原则和纲要，为患者提供从诊断、治疗到康复的全流程规范化指导。

Abstract

Cancer of unknown primary (CUP) and cancer of multiple primaries (CMP) are two groups of neoplasm with high heterogeneity

low incidence

limited clinical knowledge and evidence. The diagnosis and treatment of patients with CUP and CMP is challenging. With the progress in the radiology

pathology and genetic features of these diseases

the cooperation and development of multi-disciplinary treatment

along with the investigation of targeted and immunology treatment have updated the treatment of these patients. We intended to guide the diagnosis and treatment of patients with CUP and CMP through this guideline

providing standard guidance for the overall management of patients.

关键词

Keywords

references

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