uRT-TPS和Monaco-TPS对同一直线加速器在多癌种放射剂量计算方面差异的比较

杨彦举; 方应涛; 高大地; 王佳舟; 赵俊; 胡伟刚

doi:10.19401/j.cnki.1007-3639.2024.01.005

您当前的位置：

首页 >

文章列表页 >

uRT-TPS和Monaco-TPS对同一直线加速器在多癌种放射剂量计算方面差异的比较

论著 | 更新时间：2025-12-31

- uRT-TPS和Monaco-TPS对同一直线加速器在多癌种放射剂量计算方面差异的比较
- Comparison of radiation dose calculation differences between uRT-TPS and Monaco-TPS for the same linear accelerator in multiple cancers
- 中国癌症杂志 2024年34卷第1期页码：82-89
- 作者机构：
  
  复旦大学附属肿瘤医院放疗科，复旦大学上海医学院肿瘤学系，上海 200032
- 作者简介：
  
  [ "杨彦举（ORCID: 0000-0001-8665-6155），硕士，助理研究员。" ]
  胡伟刚（ORCID: 0000-0002-4409-6804），博士，研究员，复旦大学附属肿瘤医院放疗科副主任。
- 基金信息：
  
  国家自然科学基金(11905035)
- DOI：10.19401/j.cnki.1007-3639.2024.01.005
  中图分类号： R730.55
- 收稿：2023-08-22，
  
  修回：2023-12-28，
  
  纸质出版：2024-01-30
- 稿件说明：
移动端阅览
杨彦举, 方应涛, 高大地, 等. uRT-TPS和Monaco-TPS对同一直线加速器在多癌种放射剂量计算方面差异的比较[J]. 中国癌症杂志, 2024,34(1):82-89.

Yanju YANG, Yingtao FANG, Dadi GAO, et al. Comparison of radiation dose calculation differences between uRT-TPS and Monaco-TPS for the same linear accelerator in multiple cancers[J]. China Oncology, 2024, 34(1): 82-89.
杨彦举, 方应涛, 高大地, 等. uRT-TPS和Monaco-TPS对同一直线加速器在多癌种放射剂量计算方面差异的比较[J]. 中国癌症杂志, 2024,34(1):82-89. DOI： 10.19401/j.cnki.1007-3639.2024.01.005.

Yanju YANG, Yingtao FANG, Dadi GAO, et al. Comparison of radiation dose calculation differences between uRT-TPS and Monaco-TPS for the same linear accelerator in multiple cancers[J]. China Oncology, 2024, 34(1): 82-89. DOI： 10.19401/j.cnki.1007-3639.2024.01.005.

摘要

背景与目的：

近年来国产放疗设备及相关软件发展迅速，检验设备和软件的功能性及稳定性是必不可少的环节，本研究主要比较uRT-治疗计划系统（treatment planning system，TPS）和Monaco-TPS在常见癌症调强适形放疗（intensity-modulated radiation therapy，IMRT）计划剂量学和危及器官（organ at risk，OAR）体积计算方面的差异，评估使用uRT-TPS对Infinity直线加速器（瑞典Elekta公司）进行剂量计算的可行性。

方法：

选取直肠癌、肺癌、乳腺癌和鼻咽癌共20例患者作为研究对象，分别在uRT-TPS和Monaco-TPS中对各病例完成IMRT计划制订。在计划靶区（planning target volume，PTV）处方剂量体积相同条件下比较靶区剂量均匀性、适形性和OAR的平均剂量、最大剂量等参数。在同一直线加速器中比较验证uRT-TPS和Monaco-TPS的通过率。对比uRT-TPS和Monaco-TPS在计划跳数（monitor units，MU）、源皮距（source skin distance，SSD）和OAR的重建体积差异。

结果：

uRT-TPS和Monaco-TPS均可获得满足临床要求的放疗计划。靶区剂量具有可比拟的均匀性和适形性，uRT-TPS在靶区的最大剂量平均降低1.1 Gy（

= 0.006）。对于乳腺癌和肺癌，Monaco-TPS的正常肺组织剂量较低（

0.05）。对于鼻咽癌，uRT-TPS在口腔和咽喉的剂量指标分别降低9.2%和5.1%。uRT-TPS和Monaco-TPS的点绝对剂量（

3%）和三维面剂量（

95%）验证结果均满足临床要求。uRT-TPS感兴趣区的体积计算小于Monaco-TPS（

0.05）。

结论：

对于常见肿瘤的放疗计划，uRT-TPS可以优化出与Monaco-TPS同等水平的IMRT计划。使用uRT-TPS对Infinity直线加速器进行剂量计算具有可行性。

Abstract

Background and Purpose:

In recent years

domestic radiotherapy equipment and related software have made great progress

and testing the functionality and stability of the equipment and software is an essential step. This paper focused on comparing the differences in intensity-modulated radiation therapy (IMRT) plans dosimetry and organ at risk (OAR) volume calculations for common cancers between uRT-treatment planning system (TPS) and Monaco-TPS

and to evaluate the feasibility of dose calculation for Infinity linac (linear accelerator

Elekta

Sweden) using uRT-TPS.

Methods:

Twenty cases of rectal cancer

lung cancer

breast cancer and nasopharyngeal carcinoma were selected. The IMRT plans were completed in uRT-TPS and Monaco-TPS. The dose uniformity and conformity

mean dose

maximum dose of planning target volume (PTV) and OAR between two plans under the same prescribed dose of PTV

were compared. And the pass rates of two TPS plans validated at the same linear accelerator were compared. Meanwhile

monitor units (MU)

source skin distance (SSD) and the volume of OAR in uRT-TPS and Monaco-TPS were compared.

Results:

Wonderful plans that met the clinical requirements were obtained in uRT-TPS and Monaco-TPS. Comparable uniformity and conformability was received in PTV

and the maximum dose of PTV was reduced by 1.1 Gy for uRT-TPS (

= 0.006). For breast cancer and lung cancer

the dose in lung was lower for Monaco-TPS (

0.05). For nasopharyngeal carcinoma

the dose indicators that oral cavity and throat in the uRT-TPS was reduced by 9.2% and 5.1%

respectively. The verification results of absolute point dose (

3%) and three-dimensional surface dose (

95%) for both plans met the clinical requirements. The region of interest in uRT-TPS was smaller compared with Monaco-TPS (

0.05).

Conclusion:

A comparable IMRT plan was obtained for common tumors in uRT-TPS and Monaco-TPS. It is feasible to calculate the dose of Infinity linac using uRT-TPS.

关键词

Keywords

references

CHARLES S , MAYO . A systematic benchmark method for analysis and comparison of IMRT treatment planning algorithms [J ] . Med Dosim , 2003 , 28 ( 4 ): 235 - 242 .

王庆章 , 段天宇 , 刘建超 , 等 . Monaco与Pinnacle治疗计划系统在食管癌放疗剂量验证上的比较 [J ] . 中国医学物理学杂志 , 2017 , 34 ( 2 ): 166 - 169 .

WANG Q Z , DUAN T Y , LIU J C , et al . Comparison of Monaco and Pinnacle treatment planning systems on the dosimetric verification of radiotherapy for esophageal cancer [J ] . Chin J Med Phys , 2017 , 34 ( 2 ): 166 - 169 .

PETRIC M P , CLARK B G , ROBAR J L . A comparison of two commercial treatment-planning systems to IMRT [J ] . J Appl Clin Med Phys , 2005 , 6 ( 3 ): 63 - 80 .

VANDERSTRAETEN B , REYNAERT N , PAELINCK L , et al . Accuracy of patient dose calculation for lung IMRT: a comparison of Monte Carlo, convolution/superposition, and pencil beam computations [J ] . Med Phys , 2006 , 33 ( 9 ): 3149 - 3158 . DOI: 10.1118/1.2241992 http://doi.org/10.1118/1.2241992

KRIEGER T , SAUER O A . Monte Carlo- versus pencil-beam-/collapsed-cone-dose calculation in a heterogeneous multi-layer phantom [J ] . Phys Med Biol , 2005 , 50 ( 5 ): 859 - 868 .

王宁 , 陈阿龙 , 夏景涛 . Monaco与Xio治疗计划系统调强放疗剂量验证的比较研究 [J ] . 中国医疗设备 , 2014 ( 7 ): 20 - 22 .

WANG N , CHEN A L , XIA J T . Comparative study on the dosimetric verification of Intensity-Modulated radiation therapy of Monaco and Xio treatment planning systems [J ] . Chin Med Equip , 2014 , 29 ( 7 ): 20 - 22 .

EZZELL G A , BURMEISTER J W , DOGAN N , et al . IMRT commissioning: multiple institution planning and dosimetry comparisons, a report from AAPM Task Group 119 [J ] . Med Phys , 2009 , 36 ( 11 ): 5359 - 5373 . DOI: 10.1118/1.3238104 http://doi.org/10.1118/1.3238104

LAFOND C , GASSA F , ODIN C , et al . Comparison between two treatment planning systems for volumetric modulated arc therapy optimization for prostate cancer [J ] . Phys Med , 2014 , 30 ( 1 ): 2 - 9 . DOI: 10.1016/j.ejmp.2012.10.003 http://doi.org/10.1016/j.ejmp.2012.10.003

CLAUS F , MIJNHEER B , RASCH C , et al . Report of a study on IMRT planning strategies for ethmoid sinus cancer [J ] . Al , 2002 , 178 ( 10 ): 572 - 576 .

王佳舟 , 陈俊超 , 李龙根 , 等 . Pinnacle与Eclipse计划系统对感兴趣区体积计算的比较 [J ] . 中华放射肿瘤学杂志 , 2011 , 20 ( 2 ): 156 - 159 .

WANG J Z , CHEN J C , LI L G , et al . Comparison of region of interest volume between Pinnacle and Eclipse treatment planning system [J ] . Chin J Radiat Oncol , 2011 , 20 ( 2 ): 156 - 159 .

谭剑锋 , 邱小平 , 鲁旭尉 . Monaco与Pinnacle计划系统中感兴趣区体积的计算 [J ] . 医疗装备 , 2015 ( 15 ): 10 - 11 .

TAN J F , QIU X P , LU X W . Comparison of region of interest volume between Pinnacle and Monaco treatment planning system [J ] . Med Equip , 2015 , 28 ( 11 ): 10 - 11 .

杨金磊 , 刘博宇 , 路双臣 , 等 . Monaco与Pinnacle计划系统在肺癌容积旋转调强计划中的比较 [J ] . 中华放射医学与防护杂志 , 2015 , 35 ( 2 ): 119 - 122 .

YANG J L , LIU B Y , LU S C , et al . Comparison of Monaco and Pinnacle treatment planning systems in volumetric modulated arc therapy optimization for lung cancer [J ] . Chin J Radiol Med Prot , 2015 , 35 ( 2 ): 119 - 122 .

唐慧敏 , 杨振 , 龚学余 , 等 . 不同计划系统的剂量学比较 [J ] . 中国医学物理学杂志 , 2016 , 33 ( 3 ): 286 - 290 .

TANG H M , YANG Z , GONG X Y , et al . Dosimetric comparison of different treatment planning systems [J ] . Chin J Med Phys , 2016 , 33 ( 3 ): 286 - 290 .

MCNUTT T . Dose calculations: collapsed cone convolution superposition and delta pixel beam [R ] . Pinnacle White Paper , 2007 , ( 4535 ): 983 .

刘小波 , 汪冬 , 赵云 , 等 . KylinRay-IMRT与Pinnacle3胸部肿瘤计划剂量学比较分析 [J ] . 中国医学物理学杂志 , 2020 , 37 ( 1 ): 17 - 21 .

LIU X B , WANG D , ZHAO Y , et al . Dosimetric comparison between KylinRay-IMRT and Pinnacle3 TPS in thoracic tumor plans [J ] . Chin J Med Phys , 2020 , 37 ( 1 ): 17 - 21 .

浏览量

1953

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

暂无数据