Immunity is the basic defense barrier for body

and also closely related to the development

progression

treatment and prognosis of breast cancer. Adjuvant radiotherapy plays an important role in the multidisciplinary treatment of breast cancer. It has long been believed that radiotherapy was immunosuppressive because it could destroy the body’s immune cells directly. While recent studies have shown that radiotherapy can stimulate the host immune system in the antitumor process

including antigen processing

presentation

recognition

and eventually tumor-cell killing. In the clinical aspect

a variety of immune targeted therapies

combined with radiotherapy

have entered clinical trials. The article reviewed research progress and status of the influence of breast cancer adjuvant radiotherapy on antitumor immunity.