Background and purpose: The quality of life and psychological status of the advanced cancer patients has been widely valued. This study aimed to analyze the psychological status of the advanced cancer patients and its influence factors. Methods: The patients who were hospitalized in the palliative care department of Fudan University Cancer Center from Sep. 2011 to Mar. 2013 were included in this study. Self-rating anxiety scale(SAS)

selfrating depression scale (SDS)

EORTC QLQ-C30

social support revalued scale and symptom checklist 90 (SCL-90) were recorded and analyzed. Results: Fifty-six patients were included in this study

18 were depression and 24 were anxiety while 16 of them were depression together with anxiety. The patients were divided into 2 groups according to their psychological status. There’s no significant difference between the age and the social support between the two groups

while the mental disorders group have lower scores on body function

role function

emotional function and social function. The mental disorders were positive correlated with the symptoms score while negative correlated with the quality of life.Conclusion: There’s a high ratio of mental disorders in advanced cancer patients

the symptom scores and quality of life are related to mental disorders. We should pay more attention to the patients who were suffered more from the illness or had lower QOL scores.