孙运坡, 应学翔, 何萍青. Research progress of treatment and therapeutic target for Luminal B breast cancer[J]. China Oncology, 2015, 25(7): 555-560. DOI: 10.3969/j.issn.1007-3969.2015.07.011.
Breast cancer can be classified into 4 intrinsic subtypes by gene expression profiling: basal-like
HER-2-positive
Luminal A and Luminal B. Although Luminal cancers share similarities
the studies showed that Luminal A and B breast cancers should be perceived as distinct entities. Luminal B breast cancer has lower expression of hormone receptors
and it also exhibits worse prognosis and has a distinct profile of response to chemotherapy and endocrine therapy. This review presented the available clinical evidence for chemotherapy and endocrine therapy patterns of response