Both the incidence and mortality of colorectal cancer in China are increasing year by year. Hereditary colorectal cancer accounts for about 5%-6% of all the colorectal cancer cases

which is caused by hereditary colorectal cancer syndromes. The risk of colorectal cancer in hereditary colorectal cancer syndrome patients is significantly higher than that in general population. Fortunately

early screening and management can largely reduce cancer risk in these patients. Here

we summarize clinical and genetic features of Chinese hereditary colorectal cancer syndromes including Lynch syndrome

familial adenomatous polyposis

and Peutz-Jeghers syndrome

and review the guidelines for diagnosis and treatment in China and abroad. This paper may help people better understand hereditary colorectal cancer syndromes and facilitate accurate diagnosis and early treatment.