孙文洁, 章 真. Research progress on circulating tumor cells and their detection in colorectal cancer[J]. China Oncology, 2015, 25(11): 854-860. DOI: 10.3969/j.issn.1007-3969.2015.11.003.
Colorectal cancer is one of the most common malignant tumors. Though the development of multidisciplinary therapy has largely improved the therapy effects
many patients still died of local recurrence and metastases after surgery. Circulating tumor cell (CTC) originates from primary tumor tissues and has a close relationship with cancer metastases and prognosis. This review summarizes the CTC detection methods and relevant clinical research on CTC in recent years.