中国癌症杂志 ›› 2023, Vol. 33 ›› Issue (1): 14-24.doi: 10.19401/j.cnki.1007-3639.2023.01.002

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2022年度妇科肿瘤诊治进展

郭勤浩(), 余敏, 吴小华()   

  1. 复旦大学附属肿瘤医院妇瘤科,复旦大学上海医学院肿瘤学系,上海 200032
  • 收稿日期:2023-01-03 修回日期:2023-01-12 出版日期:2023-01-30 发布日期:2023-02-13
  • 通信作者: 吴小华(ORCID: 0000-0002-6889-3541),博士,主任医师,复旦大学附属肿瘤医院妇瘤科主任。
  • 作者简介:郭勤浩(ORCID: 0000-0003-4661-481X),博士,主治医师。
    吴小华,医学博士,教授,博士研究生导师。现任复旦大学附属肿瘤医院妇瘤科主任、妇科肿瘤多学科综合治疗组首席专家,上海市优秀学科带头人、上海市医学领军人才。现任中国抗癌协会妇科肿瘤专业委员会主任委员、中国临床肿瘤学会理事、上海市抗癌协会常务理事及妇科肿瘤专业委员会前任主任委员。曾任国际妇科癌症学会教育委员会委员、亚太地区理事候选人、美国妇科肿瘤学会国际委员会委员、美国西北大学医学院妇产科学系兼职教授等。目前还担任International Journal of Gynecological CancerCancer MedicineJournal of Gynecological Oncology、《中华妇产科杂志》、《中华解剖与临床杂志》、《中国癌症杂志》等杂志编委;美国NCCN宫颈癌和子宫内膜癌资源分层诊疗(NCCN Framework)临床指南审阅专家。

Progress in diagnosis and treatment of gynecological tumors in 2022

GUO Qinhao(), YU Min, WU Xiaohua()   

  1. Department of Gynecological Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Received:2023-01-03 Revised:2023-01-12 Published:2023-01-30 Online:2023-02-13
  • Contact: WU Xiaohua

摘要:

2022年,国家癌症中心发布的最新数据显示,中国妇科肿瘤的发病率呈上升趋势,以卵巢癌为例,年新发病例数为57 200例,粗发病率为8.47/10万,年死亡病例数为27 200例,粗死亡率达4.04/10万,发病率和死亡率均高于世标率(分别为5.59/10万和2.45/10万),中国从事妇科肿瘤防治事业的医师面临更大的挑战。妇科肿瘤在早期经过规范性治疗后整体疗效较好,但对于晚期、复发转移的患者,有限的治疗模式及高复发率往往导致预后较差。近年来,靶向治疗、免疫治疗、抗体药物偶联物治疗等新兴治疗方式开创了妇科肿瘤治疗的新纪元,为妇科肿瘤患者带来了更多治疗希望。本文总结2022年度妇科肿瘤手术治疗、放疗、化疗、靶向治疗、免疫治疗和生物标志物检测等方面的重大进展,以期更好地指导妇科肿瘤个体化精准治疗。

关键词: 宫颈癌, 卵巢癌, 子宫内膜癌, 外阴癌, 诊治进展

Abstract:

In 2022, the National Cancer Center released the latest data. The results show that the incidence of gynecologic tumors in China shows an upward trend. Taking ovarian cancer as an example, the annual number of new cases is 57 200, with a crude incidence rate of 8.47/100 000, and the annual number of death cases is 27 200, with a crude mortality rate of 4.04/100 000, and the morbidity and mortality are higher than the world standard rates (5.59/100 000 and 2.45/100 000, respectively). Physicians practicing gynecologic oncology in China face greater challenges. Patients with early gynecologic tumors have better overall outcomes after standardized treatment. However, limited treatment modalities and high recurrence rates often lead to poorer prognosis for patients with advanced, recurrent or metastatic gynecologic malignancies. In recent years, emerging treatments such as targeted therapy, immunotherapy and antibody-drug conjugate have ushered in a new era in the treatment of gynecologic tumors, bringing more hope to patients. This article summarized the significant advances in gynecological tumor surgery, radiotherapy, chemotherapy, targeted therapy, immunotherapy and biomarkers in the past year, so as to better guide the individualized and precise treatment of gynecologic tumors.

Key words: Cervical cancer, Ovarian cancer, Endometrial cancer, Vulvar cancer, Progress in diagnosis and treatment

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