中国癌症杂志 ›› 2016, Vol. 26 ›› Issue (2): 188-192.doi: 10.3969/j.issn.1007-3969.2016.02.012
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张 静，张文超，钱子君，高蓓莉，项 轶
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ZHANG Jing, ZHANG Wenchao, QIAN Zijun, GAO Beili, XIANG Yi
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摘要： 抗血管生成治疗作为肿瘤靶向治疗方式已得到临床广泛应用。抗血管生成治疗诱导的血管正常化效应机制，可以逆转肿瘤内部结构和功能异常的新生血管，改善肿瘤微环境的组织间隙高压、低氧和酸中毒，提高放化疗及免疫治疗的疗效。
关键词: 抗血管生成治疗, 血管正常化, 提高, 肿瘤治疗
Abstract: Therapeutic strategies targeting tumor angiogenesis have been approved for cancer therapy. Vasculature normalization induced by anti-angiogenic drugs can restore abnormal tumor vessels, and improve the tumor microenvironment characterized by hypoxia, extracellular acidosis, and high interstitial fluid pressure, improve the cancer treatment results by chemoradiotherapy and immunotherapy.
Key words: Anti-angiogenesis therapy, Vascular normalization, Improvement, Cancer treatment
张 静,张文超,钱子君,等. 血管正常化提高肿瘤治疗疗效[J]. 中国癌症杂志, 2016, 26(2): 188-192.
ZHANG Jing, ZHANG Wenchao, QIAN Zijun, et al. Tumor vascular normalization improves cancer treatment efficacy[J]. China Oncology, 2016, 26(2): 188-192.
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链接本文: http://www.china-oncology.com/CN/10.3969/j.issn.1007-3969.2016.02.012
http://www.china-oncology.com/CN/Y2016/V26/I2/188
