Abstract: Malignant melanoma is a high-grade malignant tumor and prone to metastasis in early stage. Patients with advanced disease have poor prognosis. The incidence of melanoma in China is increasing day by day, and patients tend to be younger. In recent years, the research on personalized tumor vaccine has made great progress and has broad application prospects. In this paper, we reviewed the research progress of personalized tumor vaccine for malignant melanoma.

Key words: Malignant melanoma, Personalized tumor vaccine, Neoantigen