中国癌症杂志 ›› 2017, Vol. 27 ›› Issue (10): 833-838.doi: 10.19401/j.cnki.1007-3639.2017.10.012

• 综述 • 上一篇    下一篇

循环肿瘤标志物在前列腺癌研究中的新进展

李高翔,杨云杰 综述,戴 波 审校   

  1. 复旦大学附属肿瘤医院泌尿外科,复旦大学上海医学院肿瘤学系,上海200032
  • 出版日期:2017-10-30 发布日期:2017-12-05
  • 通信作者: 戴 波 E-mail:bodai1978@126.com

Research progress on circulating tumor biomarkers in prostate cancer

LI Gaoxiang, YANG Yunjie, DAI Bo   

  1. Department of Urology, Fudan University Shanghai Cancer Center, and Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Published:2017-10-30 Online:2017-12-05
  • Contact: DAI Bo E-mail: bodai1978@126.com

摘要: 前列腺癌是最常见的恶性肿瘤之一,虽然前列腺特异性抗原(prostate-specific antigen,PSA)筛查、综合治疗的开展使其早期诊断、治疗疗效有较大改善,但若实现前列腺癌的个体化治疗仍亟需新的生物标志物。循环肿瘤标志物来源于肿瘤组织,与肿瘤转移及预后密切相关。该研究对循环肿瘤标志物的检测方法及其在前列腺癌研究中的新进展进行综述。

关键词: 前列腺癌, 循环肿瘤标志物, 检测, 个体化治疗

Abstract: Prostate cancer is one of the most common malignant tumors. Although (prostate-specific antigen, PSA) screening and multidisciplinary therapy had largely improved the therapy effects, new biological markers are needed to achieve individual treatment for prostate cancer. Circulating tumor biomarkers originate from primary tumor tissues and have close relationship with cancer metastases and prognosis. This review summarized the circulating tumor biomarkers detection methods and relevant clinical research in recent years.

Key words: Prostate cancer, Circulating tumor biomarkers, Detection, Individual treatment