Abstract: Wound healing results in a scar formation, especially in deep skin injury. As a result of injury in the subcutaneous tissue and skin, scar formation is coupled with surgical operation. Improvement in the knowledge about the pathological mechanism and prevention of scarring would help clinicians to better deal with postoperative care and improve the satisfaction of patients. This review put emphasis on discussing the process of scar formation after surgery and the positive factor in this process. And furthermore, This review presented primary interventions with certain therapeutic effect.

Key words: Head and neck tumor, Scar, Hypertrophic scar