China Oncology ›› 2016, Vol. 26 ›› Issue (1): 117-120.doi: 10.3969/j.issn.1007-3969.2016.01.019

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Long noncoding RNAs in urological neoplasms

ZHU Yiping, YE Dingwei   

  1. Department of Urology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Online:2016-01-30 Published:2016-02-26
  • Contact: YE Dingwei E-mail: dwyeli@163.com

Abstract: Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nt without coding capacities. Although they were initially argued to be transcriptional by-products of RNA polymerase Ⅱ, recent evidence suggests that lncRNAs have been associated with a spectrum of biological processes, and aberrant lncRNA expression may be a major contributor to tumorigenesis, progression and prognosis. This study summarizes the up-to-date studies on lncRNAs in urological neoplasms.

Key words: Long non-coding RNAs, Urological neoplasms, Gene expression