中国癌症杂志 ›› 2020, Vol. 30 ›› Issue (3): 161-165.doi: 10.19401/j.cnki.1007-3639.2020.03.001

• 专家述评与论著 • 上一篇    下一篇

乳腺癌前哨淋巴结的研究热点与评价

李 培,陈嘉健,吴 炅   

  1. 复旦大学附属肿瘤医院乳腺外科,复旦大学上海医学院肿瘤学系,上海 200032
  • 出版日期:2020-03-30 发布日期:2020-04-02
  • 通信作者: 通信作者:吴 炅 E-mail: wujiong1122@vip.sina.com

Comments on research highlights of sentinel lymph node in breast cancer

LI Pei, CHEN Jiajian, WU Jiong   

  1. Department of Breast Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Published:2020-03-30 Online:2020-04-02
  • Contact: WU Jiong E-mail: wujiong1122@vip.sina.com

摘要: 前哨淋巴结活检已成为早期乳腺癌区域淋巴结评估的标准术式。随着乳腺癌精准诊疗和预后判断的需要,临床上仍有一些问题值得深入探讨,包括新型示踪剂的临床应用、内乳前哨淋巴结活检在乳腺癌预后判断中的价值、淋巴结阳性患者新辅助治疗后豁免腋窝淋巴结清扫的安全性等。从以上几方面的问题出发,引用近期国内外相关研究结果,就这些乳腺癌前哨淋巴结的研究热点进行分析并展开讨论,以推动早期乳腺癌外科诊疗的规范化。

关键词: 乳腺癌, 前哨淋巴结, 示踪剂, 内乳淋巴结

Abstract: Sentinel lymph node biopsy has become the standard procedure for evaluating regional lymph node status in early breast cancer. In need of precision therapy and prognosis prediction for breast cancer patients, there still exist clinical issues worthy of further discussion, including clinical application of new tracers, prognostic value of internal mammary sentinel lymph node biopsy and safety profiling of exempting axillary lymph node dissection after neoadjuvant chemotherapy in node-positive patients. In this review, based on relevant articles, we fully discussed recent progress concerning the study of sentinel lymph node, which may propel a norm on surgical diagnosis and treatment of early breast cancer.

Key words: Breast cancer, Sentinel lymph node, Tracer, Internal mammary sentinel lymph node