中国癌症杂志 ›› 2013, Vol. 23 ›› Issue (8): 570-575.doi: 10.3969/j.issn.1007-3969.2013.08.002

• 专家述评 • 上一篇    下一篇

循环肿瘤细胞检测在不同阶段不同类型乳腺癌中的应用

李蕾,江泽飞   

  1. 军事医学科学院附属医院乳腺肿瘤科,北京 100071
  • 出版日期:2013-08-25 发布日期:2014-02-26
  • 通信作者: 江泽飞 E-mail:jiangzefei@medmail.com.cn

CTC detection at different stages and various subtypes of breast cancer

LI Lei,JIANG Ze-fei   

  1. Department of Breast Cancer, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China
  • Published:2013-08-25 Online:2014-02-26
  • Contact: JIANG Ze-fei E-mail: jiangzefei@medmail.com.cn

摘要: 循环肿瘤细胞(circulating tumor cell,CTC)检测在乳腺癌预后方面的应用受到了越来越多的关注。目前国内外众多大型临床研究将其贯穿于乳腺癌诊疗的各个阶段。对于不同治疗阶段的乳腺癌,CTC检测的应用价值不同,但与传统影像学相比,其在实时动态监测疾病变化、疗效评价等方面具有优势。在乳腺癌分类治疗、个体化治疗时代,CTC检测可为患者提供最及时、最优化的治疗方案。

关键词: 乳腺癌, 循环肿瘤细胞, CellSearch技术

Abstract:

The utility of circulating tumor cells in breast cancer has been paid more attention. There are many clinical trials all over the world which concerned the whole course of breast cancer. Although the value of detecting circulating tumor cells is different at each stage of breast cancer, the advantage is significant compared with traditional methods in monitoring and evaluating diseases status. Nowadays the treatments of breast cancer are classified and individualized, it is possible to find the most timely and optimized regimens after detecting the amount and characteristics of circulating tumor cells.

Key words: Breast cancer, Circulating tumor cells, CellSearch technology