中国癌症杂志 ›› 2013, Vol. 23 ›› Issue (8): 576-583.doi: 10.3969/j.issn.1007-3969.2013.08.003

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应用游离腹部皮瓣行118例乳房重建术的单中心报告

陈颖1,陈嘉莹1,李琳1,陈嘉健1,杨犇龙1,黄晓燕1,陈灿铭1,胡震1,柳光宇1,沈镇宙1,邵志敏1,俞培荣2,吴炅1   

  1. 1.复旦大学附属肿瘤医院乳腺外科,复旦大学上海医学院肿瘤学系,上海 200032;
    2.美国德克萨斯大学MD.Anderson 癌症中心整形外科,休斯顿 77030
  • 出版日期:2013-08-25 发布日期:2014-02-26
  • 通信作者: 吴炅 E-mail:wujiong1122@vip.sina.com

Single-center report of 118 cases of free abdominal flaps for breast reconstruction

CHEN Ying1,CHEN Jia-ying1,LI Lin1,CHEN Jia-jian1,YANG Ben-long1,HUANG Xiao-yan1,CHEN Can-ming1,HU Zhen1,LIU Guang-yu1,SHEN Zhen-zhou1,SHAO Zhi-min1,YU Pei-rong2,WU Jiong1   

  1. 1.Department of Breast Surgery, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;
    2.Department of Plastic Surgery, the University of Texas MD Anderson Cancer Center, Houston Texas 77030, America
  • Published:2013-08-25 Online:2014-02-26
  • Contact: WU Jiong E-mail: wujiong1122@vip.sina.com

摘要:

背景与目的:随着诊疗技术的不断革新,乳腺癌的无病生存期和总生存率显著提高。为了改善患者术后的生活质量,越来越多的乳房重建技术被应用于临床。本文拟通过回顾复旦大学附属肿瘤医院乳腺外科118例游离腹部皮瓣乳房重建术的开展情况,介绍该术式的手术方法及结果,并就开展过程中的心得体会加以阐述。方法:收集200611月—20136117(1例接受双侧重建)接受全乳切除并进行即刻或延期游离腹部皮瓣乳房重建的患者进行即刻或延期游离腹部皮瓣乳房重建的临床资料,分析手术情况、围手术期并发症发生率及远期转归。结果:在上述观察期间共完成118例游离腹部皮瓣乳房重建术,平均手术时间7.72 h,平均热缺血时间78.74 min,平均血管吻合时间60.83 min。保留腹壁下深血管穿支平均为3支,胸廓内血管为首选的受区血管。术后发生血管危象10例,其中静脉血栓6例,静脉成角4例;解救成功7例,皮瓣全部坏死3例,成功率为97.46%。术后伤口感染发生率为7.00%,下腹部膨隆发生率为3.50%,无腹壁疝发生。手术距首疗程化疗的中位时间为19 d。中位随访12个月,1例出现远处转移,未发现局部复发。结论:游离腹部皮瓣乳房重建术可获得较佳的重建乳房外观,虽然该术式较为复杂,对术者要求高,存在学习曲线,但术式成功率高,术后并发症较少,不影响肿瘤安全性,值得推广。

关键词: 乳腺癌, 乳房重建, 游离腹部皮瓣, 显微外科

Abstract:

Background and purpose: Along with the development of diagnosis and treatment technology, the disease free survival and overall survival of breast cancer have been extended. In order to improve the quality of life after mastectomy, more and more breast reconstructions were applied in breast cancer patients. We retrospectively reviewed 118 cases of free abdominal flaps for breast reconstruction performed in Fudan University Shanghai Cancer Center. Clinical outcomes, reconstructive techniques and experiences are discussed. Methods: From November, 2006 to June, 2013, we used free abdominal flaps to perform 118 cases of breast reconstruction on 117 female patients after mastectomy. We observed the surgery, complications and safety of this technic. Results: We performed 118 cases of flaps based on deep inferior epigastric vessels. The average operation time was 7.72 h. The average time of ischemia was 78.74min. The average anastomosis time was 60.83min. The average number of perforators included in the flap was 3. The internal thoracic vessels were preferred recipient vessels. Ten cases of vessel crisis occurred and 6 of them were venous thrombosis and 4 cases were venous kink. Seven of them were salvaged, and the other 3 failed, the success rate was 97.46%. Postoperative infection rate was 7.00%. Abdominal bulge occurred in 3.50% of patients. None of the patients developed abdominal hernia. The median interval between surgery and the first cycle of adjuvant chemotherapy was 19 days. The median follow-up time was 12 months. One case of distant metastasis, but no local recurrence was observed. Conclusion: Although free abdominal flap breast reconstruction requires complicated microsurgical techniques, and the learning curve does exist, free abdominal flap breast reconstruction has a high success rate with oncological safety and few complications.

Key words: Breast cancer, Breast reconstruction, Free abdominal flap, Microsurgery