中国癌症杂志 ›› 2015, Vol. 25 ›› Issue (3): 235-240.doi: 10.3969/j.issn.1007-3969.2015.03.013

• 综述 • 上一篇    

儿童和青少年甲状腺癌的治疗进展

陈嘉莹,张凌,嵇庆海   

  1. 复旦大学附属肿瘤医院头颈外科,复旦大学上海医学院肿瘤学系,上海 200032
  • 出版日期:2015-03-30 发布日期:2015-05-18
  • 通信作者: 嵇庆海 E-mail:Jiqinghai@shca.org.cn

Treatment progress of thyroid cancer in children and adolescents

CHEN Jiaying, ZHANG Ling, JI Qinghai   

  1. Department of Head and Neck, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
  • Published:2015-03-30 Online:2015-05-18
  • Contact: JI Qinghai E-mail: Jiqinghai@shca.org.cn

摘要:

   儿童和青少年甲状腺癌较为罕见。本文通过分析现有数据资料,阐述儿童和青少年甲状腺癌的治疗进展。尽管发现时分期较晚,但该病总体预后较好。手术治疗是最主要的治疗方式,目前无标准的手术处理方式。大部分外科医生赞成甲状腺全切和(或)次全切。对于单侧的低危患者,也可考虑单侧腺叶切除。预防性中央区淋巴结清扫术能够降低局部复发。在特定的患者中行放射性131I治疗能降低复发风险。由于生存期较长,在长期无瘤生存后仍可能再次复发,因此患者需要长期随访。

关键词: 甲状腺癌, 儿童和青少年, 治疗进展

Abstract:    Thyroid cancer is uncommon in children and adolescents. This article analyzed the current data and stated the treatment progress of the thyroid cancer in children and adolescents. Even though in the advanced stage at diagnosis, the prognosis is good for pediatric patients. Surgery is the treatment for pediatric thyroid cancer. Although there is no optimal surgery recommendation, most surgeons preferred total and (or) subtotal thyroidectomy. Hemithyroidectomy could also be considered in the low-risk patients with small unifocal tumors. We recommend routine central compartment clearance in pediatric thyroid cancers to reduce the local recurrence. Radioactive iodine therapy is also recommended in particular pediatric patients. Recurrences after treatment in childhood thyroid cancer may take place over a long period of time. Therefore, a life-long follow-up is mandatory.

Key words: Thyroid cancer, Children and adolescentsTreatment progress